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Drug Burden Index in Older Adults with Psychiatric Illnesses: A Cross-Sectional Study

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (2)

BackgroundMedications with anticholinergic and/or sedative properties are commonly used in the management of psychiatric illnesses. The burden of anti......

Perioperative Analgesics and Anesthesia as Risk Factors for Postoperative Chronic Opioid Use in Patients Undergoing Total Knee Arthroplasty: A Retrospective Cohort Study Using Japanese Hospital Claims Data

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (2)

BackgroundPatients with chronic postsurgical pain are commonly prescribed opioids chronically because of refractory pain although chronic opioid use c......

Signal Detection and Assessment of Herb-Drug Interactions: Saudi Food and Drug Authority SFDA Experience

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (4)

Introduction Numerous investigations on herbal medicine that have been undertaken in the past several years demonstrate the general acceptance of its ......

Safety of Brexanolone in Adults with Postpartum Depression: Postmarketing Surveillance Data

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (3)

Background Brexanolone is currently the only medication approved by the US FDA for the treatment of postpartum depression (PPD) in patients >= 15 y......

An Attempt to Replicate Randomized Trials of Diabetes Treatments Using a Japanese Administrative Claims and Health Checkup Database: A Feasibility Study

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (2)

BackgroundUse of real-world evidence (RWE) has been limited for evaluating effectiveness because of the lack of confidence in its reliability. Examini......

The Association between Deductibles and Cardiovascular Medication Adherence: A Retrospective Inception Cohort Study

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; ()

ObjectiveDrug non-adherence in primary preventive cardiovascular therapy is one of the most important modifiable drivers of cardiovascular events. The......

Persistence and Safety of Golimumab in Elderly Patients with Rheumatoid Arthritis and Renal Dysfunction in a Real-World Setting

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (1)

Background The efficacy and safety of golimumab in elderly patients with renal dysfunction are not well evaluated due to the exclusion criteria of cli......

Potential Drug-Drug Interactions Among Hospitalised Elderly Patients in Northern Sri Lanka, A Lower Middle-Income Country: A Retrospective Analysis

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (1)

Background and Objectives Elderly individuals are more vulnerable to potential drug-drug interactions (pDDIs) as age-related physiological changes, po......

A Prospective Real-World Study of Bacillus clausii Evaluating Use, Treatment Habits and Patient Satisfaction in Italian Community Pharmacies: The PEGASO Study

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; ()

Background Ailments such as diarrhoea and antibiotic-associated gut symptoms are generally self-managed using probiotics. Real-world data on reasons b......

Promise of Real-World Evidence for Patient Centricity in Gulf Cooperation Council Countries: Call to Action

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (1)

Presently, Gulf Cooperation Council countries are lagging in the generation of real-world data and use of real-world evidence for patient-centered car......

Post-Marketing Safety Study of Ramucirumab Plus FOLFIRI: Analysis of Age and Initial Dose of Irinotecan in Patients with Metastatic Colorectal Cancer

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (3)

BackgroundThere is limited real-world evidence regarding the safety of ramucirumab plus FOLFIRI in patients with metastatic colorectal cancer (mCRC).O......

Compliance with Pregnancy Prevention Recommendations for Isotretinoin Following the Amendment of the European Union Pregnancy Prevention Program: A Repeat Study in Estonia

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; ()

BackgroundIsotretinoin, indicated for severe acne, is a potent teratogen and therefore contraindicated in pregnancy. Thus, the pregnancy prevention pr......

Changing Prevalence of Medication Use in People with Cirrhosis: A Retrospective Cohort Study Using Pharmaceutical Benefits Scheme Data

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (4)

Background Safe and appropriate use of medicines is essential to improve health outcomes in cirrhosis. However, little is known about the number and t......

Multikinase Inhibitor Treatment Patterns for Advanced Thyroid Cancer in Japan: An Administrative Claims Database Study

期刊: DRUGS-REAL WORLD OUTCOMES, 2023; 10 (1)

Background The multikinase inhibitors (MKIs) sorafenib, lenvatinib, and vandetanib are approved for advanced thyroid cancer (TC) in Japan. How sequent......

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