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Mendelian randomization in the multivariate general linear model framework

期刊: GENETIC EPIDEMIOLOGY, 2022; 46 (1)

Mendelian randomization (MR) is an application of instrumental variable (IV) methods to observational data in which the IV is a genetic variant. MR me......

JIF:2.103

Full title: A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping

期刊: GENETIC EPIDEMIOLOGY, 2022; 46 (1)

Hematological measures are important intermediate clinical phenotypes for many acute and chronic diseases and are highly heritable. Although genome-wi......

JIF:2.103

Secondary analyses for genome-wide association studies using expression quantitative trait loci

期刊: GENETIC EPIDEMIOLOGY, 2022; 46 (3-4)

Genome-wide association studies (GWAS) have successfully identified thousands of single nucleotide polymorphisms (SNPs) associated with complex traits......

JIF:2.103

Deconvolution analysis of cell-type expression from bulk tissues by integrating with single-cell expression reference

期刊: GENETIC EPIDEMIOLOGY, 2022; 46 (8)

To understand phenotypic variations and key factors which affect disease susceptibility of complex traits, it is important to decipher cell-type tissu......

JIF:2.103

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