期刊: GENOME RESEARCH, 2023; 33 (4)
Density separation is a process routinely used to segregate minerals, organic matter, and even microplastics, from soils and sediments. Here we apply ......
期刊: GENOME RESEARCH, 2023; 33 (6)
Approximately 13% of the human genome at certain motifs have the potential to form noncanonical (non-B) DNA structures (e.g., G-quadruplexes, crucifor......
期刊: GENOME RESEARCH, 2023; 33 (2)
Pediatric pineoblastomas (PBs) are rare and aggressive tumors of grade IV histology. Although some oncogenic drivers are characterized, including germ......
期刊: GENOME RESEARCH, 2023; 33 (1)
Horizontal gene transfer (HGT) plays a critical role in the evolution and diversification of many microbial species. The resulting dynamics of gene ga......
期刊: GENOME RESEARCH, 2023; 33 (3)
The information about when and where each gene is to be expressed is mainly encoded in the DNA sequence of enhancers, sequence elements that comprise ......
期刊: GENOME RESEARCH, 2023; 33 (7)
Sequence-to-graph alignment is crucial for applications such as variant genotyping, read error correction, and genome assembly. We propose a novel see......
期刊: GENOME RESEARCH, 2023; 33 (7)
Compacted de Bruijn graphs are one of the most fundamental data structures in computational genomics. Colored compacted de Bruijn graphs are a variant......
期刊: GENOME RESEARCH, 2023; 33 (12)
In mammals, the adult testis is the tissue with the highest diversity in gene expression. Much of that diversity is attributed to germ cells, primaril......
期刊: GENOME RESEARCH, 2023; 33 (8)
In contrast to other mammals, the spiny mouse (Acomys) regenerates skin and ear tissue, which includes hair follicles, glands, and cartilage, in a sca......
期刊: GENOME RESEARCH, 2023; 33 (8)
Paleogenomics continues to yield valuable insights into the evolution, population dynamics, and ecology of our ancestors and other extinct species. Ho......
期刊: GENOME RESEARCH, 2023; 33 (5)
Recombination is a key molecular mechanism that has profound implications on both micro- and macroevolutionary processes. However, the determinants of......
期刊: GENOME RESEARCH, 2023; 33 (5)
The mammalian suprachiasmatic nucleus (SCN), located in the ventral hypothalamus, synchronizes and maintains daily cellular and physiological rhythms ......
期刊: GENOME RESEARCH, 2023; 33 (10)
We report the generation of an organism-wide catalog of 976,813 cis-acting regulatory elements for the bovine detected by the assay for transposase ac......
期刊: GENOME RESEARCH, 2023; 33 (4)
The rates of mutation, recombination, and transposition are core parameters in models of evolution. They impact genetic diversity, responses to ongoin......
期刊: GENOME RESEARCH, 2023; 33 (11)
Mammalian mRNA and lncRNA exons are often small compared to introns. The exon definition model predicts that exons splice autonomously, dependent on p......