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Obstetric and neonatal outcomes after natural versus artificial cycle frozen embryo transfer and the role of luteal phase support: a systematic review and meta-analysis

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (5)

BACKGROUND The number of frozen embryo transfers (FET) has increased dramatically over the past decade. Based on current evidence, there is no differe......

Endometrial receptivity in women of advanced age: an underrated factor in infertility

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (6)

BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced age is one of the critical risk factors for female-related infer......

Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (1)

BACKGROUND Modern reproductive behavior in most developed countries is characterized by delayed parenthood. Older gametes are generally less fertile, ......

SARS-CoV-2, fertility and assisted reproduction

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (2)

BACKGROUND In 2020, SARS-CoV-2 and the COVID-19 pandemic had a huge impact on the access to and provision of ART treatments. Gradually, knowledge of t......

Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (5)

BACKGROUND Endometriosis remains a poorly understood disease, despite its high prevalence and debilitating symptoms. The overlap in symptoms and the i......

Advances in non-hormonal male contraception targeting sperm motility

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (5)

BACKGROUND The high rates of unintended pregnancy and the ever-growing world population impose health, economic, social, and environmental threats to ......

Defensins: defenders of human reproductive health

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (1)

BACKGROUND Reproductive tract infection is an important factor leading to male and female infertility. Among female infertility factors, microbial and......

Contribution of semen to early embryo development: fertilization and beyond

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (4)

BACKGROUND It has long been thought that the factors affecting embryo and foetal development were exclusively maternally derived; hence, if issues reg......

Uterus transplantation: from research, through human trials and into the future

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (5)

Women suffering from absolute uterine factor infertility (AUFI) had no hope of childbearing until clinical feasibility of uterus transplantation (UTx)......

Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (2)

BACKGROUND Numerous studies have reported declines in semen quality and other markers of male reproductive health. Our previous meta-analysis reported......

Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (4)

BACKGROUND Owing to a growing number of young and adolescent Hodgkin lymphoma (HL) survivors, awareness of (long-term) adverse effects of anticancer t......

The impact of primary ciliary dyskinesia on female and male fertility: a narrative review

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (3)

BACKGROUND Primary ciliary dyskinesia (PCD) is a genetic condition affecting the structure and function of sperm flagellum and motile cilia including ......

Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (6)

BACKGROUND In IVF/ICSI treatment, the process of embryo implantation is the success rate-limiting step. Endometrial scratching has been suggested to i......

The impact of vincristine on testicular development and function in childhood cancer

期刊: HUMAN REPRODUCTION UPDATE, 2023; 29 (2)

BACKGROUND Increasing childhood cancer survival rates in recent decades have led to an increased focus on fertility as a long-term complication of can......

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