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The Interleukin-33/ST2 Axis Enhances Lung-Resident CD14+Monocyte Function in Patients with Non-Small Cell Lung Cancer

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (1)

Interleukin-33 (IL-33) binds to its cognate receptor suppression of tumorigenicity 2 (ST2), leading to critical modulatory roles in immune responses d......

Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (7)

Inflammatory bowel diseases (IBD) cause increased inflammatory signalling and oxidative damage. IBDs are correlated with an increased incidence of bra......

Role of MicroRNAs in Inflammatory Joint Diseases: A Review

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; ()

Inflammatory arthritis commonly initiates in the soft tissues lining the joint. This lining swells, as do the cells in it and inside the joint fluid, ......

Development of a Novel IgG1 Anaphylaxis Mouse Model with Uniquely Characteristic Skin Manifestations Induced Through the FcγRIII-Histamine Pathway

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (1)

Background Studies of passive anaphylaxis, in which mouse immunoglobulin G (IgG) and its antigens are administered to mice, believe that platelet-acti......

MicroRNA-211 Regulates Proliferation, Expansion, and Immune Inhibitory Function of Myeloid-Derived Suppressor Cells via Mediation of CHOP Expression

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (5)

BackgroundMyeloid-derived suppressor cells (MDSCs) are capable of effectively repressing immune responses against tumors and orchestrating the tumor m......

Cytokines Expression Compared to the Determinants of Cellular Apoptosis Prominently Attributes to the Deleterious Effects of 'A' Determinant Surface Gene Mutations in HBV Transfected Hepatoma Cell Line

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; ()

BackgroundPrevious studies have explored the role of AKT protein in anti-apoptotic/proliferative activities. However, there has been a lack of informa......

Patched 1 and C-C Motif Chemokine Receptor 6 Distinguish Heterogeneous T Helper 17 Subsets in Colitic Lamina Propria

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (2)

T helper 17 (Th17) cells contribute to the pathogenesis of inflammatory bowel diseases (IBD). However, their heterogeneity and regulatory mechanisms i......

TREM-1 as a Marker of Multiple Organ Failure in Cardiac Surgery

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (5)

Systemic inflammatory response syndrome (SIRS) frequently accompanies early postoperative period after cardiac surgery and in some cases is complicate......

Rat Experimental Autoimmune Gastritis Model

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (8)

BackgroundAutoimmune gastritis (AIG) is an autoimmune disease of the stomach characterized by the destruction of the oxyntic mucosa, which stops produ......

No Association Between Interleukin 6 and Inducible Nitric Oxide Synthase Polymorphisms and Dengue Infection: A Case-Control Study

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (2)

Background: Dengue is a life-threatening disease. The factors that lead to severe cases are not completely understood. The host immune system is invol......

All-Trans Retinoic Acid Promotes M2 Macrophage Polarization in Vitro by Activating the p38MAPK/STAT6 Signaling Pathway

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (3)

Background: M2-type macrophages are inflammation-suppressing cells that are differentiated after induction by cytokines such as IL-4 or IL-13, which p......

Study of NLRP3 Single Nucleotide Polymorphisms in Juvenile Systemic Lupus Erythematosus (JSLE)

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; 52 (5)

Juvenile systemic lupus erythematosus (JSLE) is a multifaceted multifactorial disorder with an unclear etiopathogenesis. Environmental factors, geneti......

The Multifunction Role of Tumor-Associated Mesenchymal Stem Cells and Their Interaction with Immune Cells in Breast Cancer

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; ()

Mesenchymal stem cells (MSCs) are a heterogeneous group of progenitor cells that play a multifunctional role including tissue regeneration, self-renew......

A Comparative Transcriptomic Study and Key Gene Targeting of Lamprey Gonadal Immune Response

期刊: IMMUNOLOGICAL INVESTIGATIONS, 2023; ()

The mammalian testis and ovary possess special immunocompetence, which is central to provide protection against pathogens. However, the innate immune ......

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