期刊： IMMUNOLOGICAL REVIEWS, 2023; 313 (1)
The complement system plays an important pathophysiologic role in human diseases associated with immune or ischemic insults. In addition to understand......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 313 (1)
The model of the solid organ as a target for circulating complement deposited at the site of injury, for many years concealed the broader influence of......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 313 (1)
Dysregulation of the alternative complement pathway predisposes individuals to a number of diseases. It can either be evoked by genetic alterations in......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 314 (1)
While fundamental in their innate role in combating infection and responding to injury, neutrophils are emerging as key modulators of adaptive immune ......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 316 (1)
The human skin is populated by a diverse pool of memory T cells, which can act rapidly in response to pathogens and cancer antigens. Tissue-resident m......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 320 (1)
Since their discovery, CD4(+)CD25(hi)FOXP3(hi) regulatory T cells (Tregs) have been firmly established as a critical cell type for regulating immune h......
期刊： IMMUNOLOGICAL REVIEWS, 2023; ()
Fungi are opportunists: They particularly require a defect of immunity to cause severe or disseminated disease. While often secondary to an apparent i......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 314 (1)
The burst of superoxide produced when neutrophils phagocytose bacteria is the defining biochemical feature of these abundant immune cells. But 50 year......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 315 (1)
The Innate Lymphoid Cell (ILC) family is a relatively recently described immune cell family involved in innate immune responses and tissue homeostasis......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 316 (1)
Memory T cells form an essential part of immunological memory, which can last for years or even a lifetime. Much experimental work has shown that the ......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 316 (1)
Tissue-resident memory T cells (T-RM) are considered to be central to maintaining mucosal barrier immunity and tissue homeostasis. Most of this knowle......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 320 (1)
Cytokines have long been considered promising cancer immunotherapy agents due to their endogenous role in activating and proliferating lymphocytes. Ho......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 314 (1)
The principle of trained immunity represents innate immune memory due to sustained, mainly epigenetic, changes triggered by endogenous or exogenous st......
期刊： IMMUNOLOGICAL REVIEWS, 2023; 313 (1)
C3 is the central effector molecule of the complement system, mediating its multiple functions through different binding sites and their corresponding......
