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Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (1)

PURPOSE. To reveal the role of cold-sensing transient receptor potential melastatin 8 METHODS. Cold sensitivity, tear production, corneal thickness, a......

Choroidal Microvasculature Dropout in the Absence of Parapapillary Atrophy in POAG

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (3)

PURPOSE. To describe the parapapillary choroidal microvasculature dropout (CMvD) in glaucomatous eyes without beta-zone parapapillary atrophy (beta-PP......

The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (7)

PURPOSE. To identify the expression of the mechanosensitive ion channel Piezo1 in the retina of guinea pigs with form deprivation myopia (FDM) and to ......

Association of Polymorphisms in ZFHX1B and PAX6 With Anisometropia in Chinese Children: The Hong Kong Children Eye Genetics Study

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (7)

PURPOSE. To identify gene variants associated with anisometropia development in children.METHODS. This is a population-based, cross-sectional, and lon......

CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (7)

PURPOSE. CD40 is upregulated in the retinas of diabetic mice, drives pro-inflammatory molecule expression, and promotes diabetic retinopathy. The role......

Photoreceptor-Specific Temporal Contrast Sensitivities in RP1L1-Associated Occult Macular Dystrophy

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (7)

PURPOSE. The purpose of this study was to compare L-, M-, S-cone-, and rod-driven temporal contrast sensitivities (tCS) in patients with RP1L1-associa......

Randomized Trial of Treat-and-Extend Intravitreal Aflibercept for Radiation Retinopathy: 1-Year Outcomes

期刊: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023; 64 (7)

PURPOSE. Radiation retinopathy (RR)-related macular edema commonly causes poor visual acuity outcomes in patients previously treated with ocular radia......

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