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Msi2-mediated MiR7a-1 processing repression promotes myogenesis

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (1)

Background Most of the microRNAs (MiRs) involved in myogenesis are transcriptional regulated. The role of MiR biogenesis in myogenesis has not been ch......

JIF:10.029

Computed tomography-defined body composition as prognostic markers for unfavourable outcomes and in-hospital mortality in coronavirus disease 2019

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (1)

Background Low skeletal muscle mass (LSMM) and visceral fat areas can be assessed by cross-sectional images. These parameters are associated with seve......

JIF:10.029

Impact of protocol-based physiotherapy on insulin sensitivity and peripheral glucose metabolism in critically ill patients

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (2)

Background The impact of physiotherapy on insulin sensitivity and peripheral glucose metabolism in critically ill patients is not well understood. Met......

JIF:10.029

Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (2)

Background Histone deacetylase 4 (HDAC4) is a stress-responsive factor that mediates multiple cellular responses. As a member of class IIa HDACs, HDAC......

JIF:10.029

Changes in predicted lean body mass, appendicular skeletal muscle mass, and body fat mass and cardiovascular disease

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (2)

Background Little is known about the association of changes in two body components, muscle and fat mass, with the risk of cardiovascular disease (CVD)......

JIF:10.029

Gut microbes and muscle function: can probiotics make our muscles stronger?

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (3)

Evidence suggests that gut microbiota composition and diversity can be a determinant of skeletal muscle metabolism and functionality. This is true in ......

JIF:10.029

Autophagy in muscle regeneration: potential therapies for myopathies

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (3)

Autophagy classically functions as a physiological process to degrade cytoplasmic components, protein aggregates, and/or organelles, as a mechanism fo......

JIF:10.029

Gut microbial characteristics in poor appetite and undernutrition: a cohort of older adults and microbiota transfer in germ-free mice

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (4)

Background Older adults are particularly prone to the development of poor appetite and undernutrition. Possibly, this is partly due to the aged gut mi......

JIF:10.029

Myosteatosis as an independent risk factor for mortality after kidney allograft transplantation: a retrospective cohort study

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (1)

Background Patients with end-stage renal disease may display both a loss of skeletal muscle mass and an increase in muscle fat deposits. We aimed to a......

JIF:10.029

A systematic review examining the relationship between cytokines and cachexia in incurable cancer

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (2)

Cancer cachexia is an unmet clinical need that affects more than 50% of patients with cancer. The systemic inflammatory response, which is mediated by......

JIF:10.029

m(6)A demethylase ALKBH5 drives denervation-induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (2)

Background Skeletal muscle atrophy is a common clinical manifestation of various neurotrauma and neurological diseases. In addition to the treatment o......

JIF:10.029

Inhibition of epidermal growth factor receptor suppresses parathyroid hormone-related protein expression in tumours and ameliorates cancer-associated cachexia

期刊: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022; 13 (3)

Background Lung cancer is the primary cause of cancer deaths worldwide. Activation of epidermal growth factor receptor (EGFR) leads to lung cancer pro......

JIF:10.029

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