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Ovariectomy Reduces Vasocontractile Responses of Rat Middle Cerebral Arteries After Focal Cerebral Ischemia

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (1)

Effects of sex hormones on stroke outcome are not fully understood. A deleterious consequence of cerebral ischemia is upregulation of vasoconstrictor ......

JIF:2.345

Selatogrel: A Novel Subcutaneous P2Y(12) Inhibitor

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (2)

The use of a P2Y(12) inhibitor as a component of dual antiplatelet therapy in patients with an acute coronary syndrome (ACS) is well established. Howe......

JIF:2.345

Ivabradine and Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (4)

This was a meta-analysis of randomized control trials (RCTs) to evaluate the effect of ivabradine on the risk of atrial fibrillation (AF) and its effe......

JIF:2.345

Sex Differences in Low-Density Lipoprotein Cholesterol Reduction With PCSK9 Inhibitors in Real-world Patients: The LIPID-REAL Registry

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (4)

Background: Previous evidence supports that monoclonal antibodies that inhibit the proprotein convertase subtilisin/kexin type 9 (PCSK9) reduce low-de......

JIF:2.345

Effect of Channel Assembly (KCNQ1 or KCNQ1+KCNE1) on the Response of Zebrafish I-Ks Current to I-Ks Inhibitors and Activators

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (5)

In cardiac myocytes, the slow component of the delayed rectifier K+ current (I-Ks) ensures repolarization of action potential during beta-adrenergic a......

JIF:2.345

Inhibition of PIKfyve Ameliorates the Proliferation and Migration of Vascular Smooth Muscle Cells and Vascular Intima Hyperplasia By Reducing mTORC1 Activity

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (5)

This study was designed to investigate the role and mechanism of PIKfyve in the proliferation and migration of vascular smooth muscle cells (VSMCs) an......

JIF:2.345

Consideration Regarding the Analysis of Randomized Controlled Trials in the Era of Evidence-based Medicine

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (5)

Analysis of randomized controlled trials (RCTs) is the cornerstone of evidence-based medicine, therapeutic guidelines and ultimately daily practice. H......

JIF:2.345

Dapagliflozin Attenuates Contrast-induced Acute Kidney Injury by Regulating the HIF-1 alpha/HE4/NF-kappa B Pathway

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (6)

Contrast-induced acute kidney injury (CI-AM) causes clinically acquired nephropathy in patients who undergo coronary interventions. Hypoxic injury to ......

JIF:2.345

R-spondin 3 Inhibits High Glucose-Induced Endothelial Activation Through Leucine-Rich G Protein-Coupled Receptor 4/Wnt/beta-catenin Pathway

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (1)

High glucose-induced endothelial activation plays critical roles in the development of diabetic vascular complications. R-spondin 3 could inhibit infl......

JIF:2.345

Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (3)

Understanding the activation of G protein-coupled receptors (GPCRs) is of paramount importance to the field of cardiovascular medicine due to the crit......

JIF:2.345

Role of Circadian Rhythm and Impact of Circadian Rhythm Disturbance on the Metabolism and Disease

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 79 (3)

Molecular circadian clocks exist in almost all cells of the organism and operate for approximately 24 hours, maintain the normal physiological and beh......

JIF:2.345

Atorvastatin Ameliorates Doxorubicin-Induced Cardiomyopathy by Regulating the Autophagy-Lysosome Pathway and Its Upstream Regulatory Factor Transcription Factor EB

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (5)

Doxorubicin is a widely used anticancer drug in clinical practice, and its myocardial toxicity is the main concern in oncotherapy. Statins are commonl......

JIF:2.345

The Functional Effects of Visfatin on Human Left Internal Mammary Artery

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (5)

Visfatin may play a role in vascular dysfunction in metabolic disorders. Apart from its insulin-mimetic actions, it has divergent actions in the cardi......

JIF:2.345

Polypharmacy and Major Adverse Events in Atrial Fibrillation

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (6)

Atrial fibrillation is the most common arrhythmia, ranging from 0.1% in patients < 55 years to > 9% in octogenarian patients. Polypharmacotherap......

JIF:2.345

Dofetilide Dose Reductions and Discontinuation in Obese Compared with Nonobese Patients

期刊: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022; 80 (6)

Dofetilide is an antiarrhythmic agent and primarily eliminated renally. Initial dosing is determined by creatinine clearance, calculated by total body......

JIF:2.345

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