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Practicality of STAT3 Gene Polymorphisms and Sorafenib Trough Concentration as Biomarkers for Sorafenib-Induced Hand-Foot Skin Reaction in Hepatocellular Carcinoma

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Introduction. The aim of this study was to evaluate the practicality of the signal transducer and activator of transcription (STAT) 3 polymorphisms as......

Efficacy and Safety of the Intraoperative Application of Mitomycin in Glaucoma Patients with Trabeculectomy: A Systematic Review and Meta-Analysis

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

What Is Known and Objective. The primary cause of trabeculectomy failure in glaucoma surgery is the imperfect formation of the filter bubble, which bl......

Adverse Reaction Signals Mining of Vonoprazan: A Pharmacovigilance Study Based on FAERS

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Background. Vonoprazan is a novel selective and noncompetitive oxidative-reduction state proton pump inhibitor (PPI), known as a potassium-competitive......

Neuromuscular Blocking Agents and Cancer: A Narrative Review

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Objective. Neuromuscular blocking agents (NMBAs) are part of the three elements of general anaesthesia (sedation, analgesia, and muscle relaxation), w......

Preparation and Evaluation of Onjisaponin B-Loaded Liposomes for Drug Delivery to Enhance Mitochondrial Function and Rescue Parkinson's Disease by Activating Mitophagy

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Onjisaponin B (OB) is the main active ingredient of Radix Polygalae with various bioactivities. However, the protective effect of OB in Parkinson's di......

A Real-World Safety Analysis of Upadacitinib Based on FDA Adverse Event Reporting System (FAERS)

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Objectives. To investigate adverse events (AEs) associated with upadacitinib in the real world using data mining from the FDA Adverse Event Reporting ......

Effect of Integrated Treatment with Traditional Chinese Medicine on Hashimoto's Thyroiditis Patients

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

What is Known and Objective. To explore the effects of traditional Chinese medicine (TCM) combined with levothyroxine (L-T4) on thyroid autoantibodies......

Factors Influencing Blood Concentration of Voriconazole and Therapeutic Drug Monitoring in Patients with Child-Pugh Class C Cirrhosis

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

What Is Known and Objective. CYP2C19 is an important influencing factor for voriconazole trough plasma concentration (C-min); however, it is not verif......

Antimicrobial Resistance and Biofilm Production in Uropathogens from Renal Disease Patients Admitted to Tribhuvan University Teaching Hospital, Nepal

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Background. Various antibiotics are prescribed empirically by physicians to cope with infections in renal disease patients. A urinary tract infection ......

Insights from the Analysis of the Sepsis Dataset: Understanding the Immune Dynamics and Molecular Pathways in Sepsis

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Sepsis, a critical medical condition instigated by infections, profoundly alters molecular and cellular immune responses. This study focused on the GS......

Continuous Improvement of the Rational Use of Central Nervous System Disease-Related Drugs in Elderly Inpatients

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

What Is Known? In elderly inpatients, potential inappropriate medication (PIM) is a prominent prescription challenge. However, there is limited inform......

The Survival Effect of Metformin on Non-Small Cell Lung Cancer Treated with Chemotherapy: A Systematic Review

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

Objective. Metformin is a common antidiabetic drug that has been reported to serve as an anticancer agent in combination with other therapies. But the......

Eugenia supra-axillaris Essential Oil and Its Nanoemulsion: Chemical Characterization, In Vivo Anti-Inflammatory, Analgesic, and Antipyretic Activities

期刊: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2023; 2023 ()

The use of standard synthetic medications to treat inflammatory illnesses is associated with several negative effects. It has been shown that medicina......

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