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Treatment and comorbidity burden among people living with HIV: a review of systematic literature reviews

期刊: JOURNAL OF DRUG ASSESSMENT, 2023; 12 (1)

Background As the human immunodeficiency virus (HIV) treatment landscape continues to evolve, the prolonged life expectancy and long-term exposure to ......

Vasoactive pharmacologic therapy in cardiogenic shock: a critical review

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Background Cardiogenic shock (CS) is an acute complex condition leading to morbidity and mortality. Vasoactive medications, such as vasopressors and i......

Intravitreal vascular endothelial growth factor (VEGF) inhibitor injection in patient during pregnancy

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Purpose: To report the clinical course of a woman treated with intravitreal bevacizumab during pregnancy. Case report: A 27-year-old female with poorl......

Adherence to cystic fibrosis transmembrane conductance regulator (CFTR) modulators: analysis of a national specialty pharmacy database

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Background: There have been significant advances in Cystic Fibrosis (CF) treatment, with the introduction of Cystic Fibrosis Transmembrane Conductance......

Seizure clusters

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Acute repetitive seizures, also called seizure clusters, are common phenomena in patients with epilepsy. They are a burden on patients and their careg......

Efficacy and safety of timolol-dorzolamide fixed-combination three times a day versus two times a day in newly diagnosed open-angle glaucoma

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Objective: This study aimed to compare the therapeutic efficacy and safety of dorzolamide/timolol fixed-combination(Cosopt) in newly diagnosed primary......

Prevalence of Helicobacter pylori infection and the incidence of the associated malignant and peptic ulcer disease (PUD) at Nelson Mandela Academic Hospital: a retrospective analysis

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Background: H. pylori infection is associated with both benign and malignant gastrointestinal diseases. However, no studies have been conducted locall......

Use of oral rivaroxaban in cerebral venous thrombosis

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Background: Cerebral venous thrombosis (CVT) is an uncommon cause of stroke in humans and the mainstay of treatment is anticoagulation unless contrain......

Hereditary angioedema patients would prefer newer-generation oral prophylaxis

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Objective To explore treatment preferences of patients with Hereditary Angioedema (HAE), a debilitating disorder characterized by potentially life-thr......

The relationship between Eastern Cooperative Oncology Group performance status and healthcare resource utilization among patients with advanced or metastatic colorectal, lung or gastric cancer

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Aims: The ability of a patient to receive anti-cancer treatment depends on a variety of factors, including performance status (PS), which is typically......

Review of cyclin-dependent kinase 4/6 inhibitors in the treatment of advanced or metastatic breast cancer

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Objective The purpose of this study is to review CDK 4/6 inhibitors used to treat metastatic breast cancer for patient safety, cost and utilization. B......

A systematic evidence-based review of treatments for primary hyperhidrosis

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Objective: Hyperhidrosis (excessive sweating) is associated with significant quality-of-life burden yet is often undertreated. With limited FDA-approv......

Exploring the burden of short-term CHOP chemotherapy adverse events in post-transplant lymphoproliferative disease: a comprehensive literature review in lymphoma patients

期刊: JOURNAL OF DRUG ASSESSMENT, 2021; 10 (1)

Purpose: Cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) is a treatment for post-transplant lymphoproliferative disease (PTLD) following......

Efficacy of lofexidine for mitigating opioid withdrawal symptoms: results from two randomized, placebo-controlled trials

期刊: JOURNAL OF DRUG ASSESSMENT, 2020; 9 (1)

Objectives: Fear of opioid withdrawal syndrome (OWS) often dissuades opioid discontinuation. Lofexidine is an FDA-approved, alpha(2)-adrenergic recept......

Comparison of readmissions among hospitalized nonvalvular atrial fibrillation patients treated with oral anticoagulants in the United States

期刊: JOURNAL OF DRUG ASSESSMENT, 2020; 9 (1)

Objectives: To compare the risks of 1-month all-cause, major bleeding (MB)-related and stroke-related readmissions and the associated hospital resourc......

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