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Sequential targeting dual-responsive magnetic nanoparticle for improved therapy of lung metastatic breast cancer

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (6)

Lung metastatic breast cancer is a leading cause of cancer-related death in women and difficult to treat due to non-specific drug delivery. Herein a s......

Relationship between ferroptosis and mitophagy in renal fibrosis: a systematic review

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (8)

Renal fibrosis, characterised by glomerulosclerosis and tubulointerstitial fibrosis, is a typical pathological alteration in the progression of chroni......

ceRNA networks in gynecological cancers progression and resistance

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (9)

Gynecological cancers are the second most common types of cancer in women. Clinical diagnosis of these cancers is often delayed or misdiagnosed due to......

The activation of SIRT1 by resveratrol reduces breast cancer metastasis to lung through inhibiting neutrophil extracellular traps

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (9)

Neutrophil extracellular traps (NETs) play a crucial role in breast cancer metastasis. However, the therapeutic target of NETs in breast cancer metast......

Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (3)

In recent years, there have been many exciting developments in the biomedical applications of the macrophage membrane bionic drug delivery system (MM-......

Impact of tumoral structure and bacterial species on growth and biodistribution of live bacterial therapeutics in xenografted tumours

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (2)

Live bacterial therapeutics is gaining attention, especially for cancer therapy, because anaerobic bacteria selectively grow inside the solid tumours.......

Stimulus-responsive peptide hydrogels: a safe and least invasive administration approach for tumor treatment

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (7)

Tumours, with increasing mortality around the world, have bothered human beings for decades. Enhancing the targeting of antitumor drugs to tumour tiss......

Targeted delivery of epirubicin to cancerous cell using copper sulphide nanoparticle coated with polyarginine and 5TR1 aptamer

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (9)

Chemotherapy has been widely acknowledged as a primary approach for cancer treatment. However, the administration of chemotherapy agents is often limi......

Signalling in pancreatic cancer: from pathways to therapy

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (10)

Pancreatic cancer (PC) is a common malignant tumour in the digestive system. Due to the lack of sensitive diagnostic markers, strong metastasis abilit......

Angiopep-2 modified dual drug-loaded liposomes with brain targeting functionality mitigate Alzheimer's disease-related symptoms in APP/PS-1 mice

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (6)

The blood-brain barrier (BBB) is a barrier that maintains brain homeostasis, but it is also one of the major problems that must be overcome in the dev......

Nanotechnology revolutionises breast cancer treatment: harnessing lipid-based nanocarriers to combat cancer cells

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (8)

One of the most common cancers that occur in females is breast cancer. Despite the significant leaps and bounds that have been made in treatment of br......

Recent developments in nanoparticles for the treatment of diabetes

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (9)

Changes in the homeostasis of blood sugar levels are a hallmark of diabetes mellitus, an incurable metabolic condition, for which the first-line treat......

Microanatomy of the metabolic associated fatty liver disease (MAFLD) by single-cell transcriptomics

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (4)

BackgroundMetabolic-associated fatty liver disease (MAFLD) is a major cause of liver disease worldwide and comprises non-alcoholic fatty liver (NAFL) ......

A critical review on the role of nanotheranostics mediated approaches for targeting β amyloid in Alzheimer's

期刊: JOURNAL OF DRUG TARGETING, 2023; 31 (7)

Alzheimer's is one of the most common neurodegenerative illnesses that affect brain cellular function. In this disease, the neurons in the brain are c......

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