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Discovery of Teleost Plasma Kallikrein/Coagulation Factor XI-Like Gene from Channel Catfish (Ictalurus punctatus) and the Evidence that the Protein Encoded by it Acts as a Lectin

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (4)

Mammalian plasma kallikrein (PK) and coagulation factor XI (fXI) are serine proteases that play in the kinin-kallikrein cascade and in the blood clott......

Tracking the Diversity and Chromosomal Distribution of the Olfactory Receptor Gene Repertoires of Three Anurans Species

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (6)

Olfaction is a crucial capability for most vertebrates and is realized through olfactory receptors in the nasal cavity. The enormous diversity of olfa......

Structural Characterization of the Chlorophyllide a Oxygenase (CAO) Enzyme Through an In Silico Approach

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (2)

Chlorophyllide a oxygenase (CAO) is responsible for converting chlorophyll a to chlorophyll b in a two-step oxygenation reaction. CAO belongs to the f......

Unusual Evolution of Cephalopod Tryptophan Indole-Lyases

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (6)

Tryptophan indole-lyase (TIL), a pyridoxal-5-phosphate-dependent enzyme, catalyzes the hydrolysis of l-tryptophan (l-Trp) to indole and ammonium pyruv......

Pangenomic Analysis of Nucleo-Cytoplasmic Large DNA Viruses. I: The Phylogenetic Distribution of Conserved Oxygen-Dependent Enzymes Reveals a Capture-Gene Process

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; ()

The Nucleo-Cytoplasmic Large DNA Viruses (NCLDVs) infect a wide range of eukaryotic species, including amoeba, algae, fish, amphibia, arthropods, bird......

Exploring Flexibility and Folding Patterns Throughout Time in Voltage Sensors

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (6)

The voltage-sensing domain (VSD) is a module capable of responding to changes in the membrane potential through conformational changes and facilitatin......

Evolution of TOP1 and TOP1MT Topoisomerases in Chordata

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (2)

Type IB topoisomerases relax the torsional stress associated with DNA metabolism in the nucleus and mitochondria and constitute important molecular ta......

Evolutionary Consequences of Functional and Regulatory Divergence of HD-Zip I Transcription Factors as a Source of Diversity in Protein Interaction Networks in Plants

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (5)

The HD superfamily has been studied in detail for several decades. The plant-specific HD-Zip I subfamily attracts the most attention because of its in......

Barcoding Populations of Pseudomonas fluorescens SBW25

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (3)

In recent years, evolutionary biologists have developed an increasing interest in the use of barcoding strategies to study eco-evolutionary dynamics o......

Domain Architecture Based Methods for Comparative Functional Genomics Toward Therapeutic Drug Target Discovery

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (5)

Genes duplicate, mutate, recombine, fuse or fission to produce new genes, or when genes are formed from de novo, novel functions arise during evolutio......

Evolutionary Aspects of Selenium Binding Protein (SBP)

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (4)

Selenium-binding proteins represent a ubiquitous protein family and recently SBP1 was described as a new stress response regulator in plants. SBP1 has......

Left-Right Reversal Recurrently Evolved Regardless of Diaphanous-Related Formin Gene Duplication or Loss in Snails

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (5)

Bilateria exhibit whole-body handedness in internal structure. This left-right polarity is evolutionarily conserved with virtually no reversed extant ......

PAReTT: A Python Package for the Automated Retrieval and Management of Divergence Time Data from the TimeTree Resource for Downstream Analyses

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (4)

Evolutionary processes happen gradually over time and are, thus, considered time dependent. In addition, several evolutionary processes are either ada......

Decay of Skin-Specific Gene Modules in Pangolins

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (4)

The mammalian skin exhibits a rich spectrum of evolutionary adaptations. The pilosebaceous unit, composed of the hair shaft, follicle, and the sebaceo......

A Micro-evolutionary Change in Target Binding Sites as a Key Determinant of Ultrabithorax Function in Drosophila

期刊: JOURNAL OF MOLECULAR EVOLUTION, 2023; 91 (5)

Hox genes encode Homeodomain-containing transcription factors, which specify segmental identities along the anterior-posterior axis. Functional change......

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