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Identification of liquid biopsy-based mutations in colorectal cancer by targeted sequencing assays

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 67 ()

Recently, liquid biopsy, as a promising approach was introduced for the analysis of different tumor-derived circulating markers including tumor DNA an......

Variable fragment length allele-specific polymerase chain reaction (VFLASP), a method for simple and reliable genotyping

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 69 ()

Single-nucleotide polymorphism (SNP) is a substitution of a single nucleotide at a specific position in the genome. Until now, 585 million SNPs have b......

Interrelationship of hemoglobin A1c level lipid profile, uric acid, C-reactive protein levels and age in a large hospital database

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 72 ()

Introduction: Hemoglobin A1c (HbA1c) is used to monitor glucose homeostasis and to identify risk for diabetes. As diabetic patients are frequently pre......

Prenatal and postnatal genetic testing toward personalized care: The non-invasive perinatal testing

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 72 ()

This article investigates how non-invasive prenatal testing and the incorporation of genomic sequencing into newborn screening postnatally are transfo......

Evaluation of the expression level of some coding and non-coding genes in oral squamous cell carcinoma

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 70 ()

Introduction: Oral squamous cell carcinoma (OSCC) is the most common cancers arising from the head and neck region. There is growing evidence that lnc......

Clonal diversity in KRAS mutant colorectal adenocarcinoma under treatment: Monitoring of cfDNA using reverse hybridization and DNA sequencing platforms

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 67 ()

Biological heterogeneity is a key feature of malignancies that significantly contributes to disease progression and therapy resistance. Residual/relap......

Evaluation of the immune checkpoint factors in idiopathic membranous nephropathy

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 69 ()

Idiopathic membranous nephropathy (IMN), a single-organ autoimmune disease, is recognized by autoantibodies to podocyte proteins and identified as the......

Current landscape of miRNAs and TGF-β signaling in lung cancer progression and therapeutic targets

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 72 ()

Lung cancer (LC) is the primary reason for cancer-associated fatalities globally. Due to both tumor-suppressing and tumor-promoting activities, the TG......

Non-coding RNA profile for natural killer cell activity

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 72 ()

Natural killer cells (NK cells) are a type of cytotoxic lymphocytes which are involved in innate immunity, alongside with assisting with adaptive immu......

DNA in fresh urine supernatant is not affected by additional centrifugation and is protected against deoxyribonuclease

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 68 ()

Urinary DNA is widely studied as a non-invasive marker for monitoring of kidneys after transplantation or the progression of urinary tract tumors. The......

Introduced the ITGB1-DT as a novel biomarker associated with five potential drugs using bioinformatics analysis of breast cancer proteomics data and RT-PCR

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 71 ()

Background: Breast cancer (BC) has been identified as a significant contributor to the rising number of female cancer deaths. As, it has become clear ......

First trimester prediction models for small-for- gestational age and fetal growth restricted fetuses without the presence of preeclampsia

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 72 ()

We established efficient first trimester prediction models for small-for-gestational age (SGA) and fetal growth restriction (FGR) without the presence......

Venous thromboembolism-related genetic determinant F11 rs4253417 is a potential prognostic factor in ischaemic stroke

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 70 ()

Ischaemic stroke (IS) and venous thromboembolism (VTE) are two forms of thromboembolism that, although distinct, seem to share numerous risk factors. ......

Extracellular vesicles derived from dental mesenchymal stem/stromal cells with gemcitabine as a cargo have an inhibitory effect on the growth of pancreatic carcinoma cell lines in vitro

期刊: MOLECULAR AND CELLULAR PROBES, 2023; 67 ()

Extracellular vesicles (EVs) are nowadays a target of interest in cancer therapy as a successful drug delivering tool. Based on their many beneficial ......

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