期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (5)
Bacteria provide a rich source of natural products with potential therapeutic applications, such as novel antibiotic classes or anticancer drugs. Bioa......
期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (1)
Integrins are cell adhesion and signalling proteins crucial to a wide range of biological functions. Effective marketed treatments have successfully t......
期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (6)
Psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have emerging therapeutic potential for neuropsychiatric diseases such as de......
期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (10)
The potential of therapeutically targeting RNA structures with small molecules is being increasingly recognized. Here, Disney and colleagues review st......
期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (12)
MYC, one of the most commonly dysregulated proteins in cancer, has long seemed 'undruggable'. Can a clinical-stage cell-penetrating peptide - or precl......
期刊： NATURE REVIEWS DRUG DISCOVERY, 2022; 21 (1)
John Maraganore, departing CEO of Alnylam Pharmaceuticals, discusses 20 years of RNAi drug development, new public health opportunities, remaining del......
