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Perineuronal Nets: Subtle Structures with Large Implications

期刊: NEUROSCIENTIST, 2023; 29 (5)

Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround the soma and proximal dendrites of certain neurons in th......

Insights into Enhancer RNAs: Biogenesis and Emerging Role in Brain Diseases

期刊: NEUROSCIENTIST, 2023; 29 (2)

Enhancers are cis-acting elements that control the transcription of target genes and are transcribed into a class of noncoding RNAs (ncRNAs) termed en......

Glutaminolysis and the Control of Neural Progenitors in Neocortical Development and Evolution

期刊: NEUROSCIENTIST, 2023; 29 (2)

Multiple types of neural progenitor cells (NPCs) contribute to the development of the neocortex, a brain region responsible for our higher cognitive a......

The Endoplasmic Reticulum and Its Contacts: Emerging Roles in Axon Development, Neurotransmission, and Degeneration

期刊: NEUROSCIENTIST, 2023; ()

The neuronal endoplasmic reticulum (ER) consists of a dynamic, tubular network that extends all the way from the soma into dendrites, axons, and synap......

Targeted Optical Neural Stimulation: A New Era for Personalized Medicine

期刊: NEUROSCIENTIST, 2023; 29 (2)

Targeted optical neural stimulation comprises infrared neural stimulation and optogenetics, which affect the nervous system through induced thermal tr......

Do Endocannabinoids Cause the Runner's High? Evidence and Open Questions

期刊: NEUROSCIENTIST, 2023; 29 (3)

The runner's high is an ephemeral feeling some humans experience during and after endurance exercise. Recent evidence in mice suggests that a runner's......

Influencing Human Behavior with Noninvasive Brain Stimulation: Direct Human Brain Manipulation Revisited

期刊: NEUROSCIENTIST, 2023; 29 (3)

The use of tools to perturb brain activity can generate important insights into brain physiology and offer valuable therapeutic approaches for brain d......

BDNF: New Views of an Old Player in Traumatic Brain Injury

期刊: NEUROSCIENTIST, 2023; ()

Traumatic brain injury is a common health problem affecting millions of people each year. BDNF has been investigated in the context of traumatic brain......

The Dual Nature of Microglia in Alzheimer's Disease: A Microglia-Neuron Crosstalk Perspective

期刊: NEUROSCIENTIST, 2023; 29 (5)

Microglia are critical players in the neuroimmune system, and their involvement in Alzheimer's disease (AD) pathogenesis is increasingly being recogni......

The Cerebellum and the Motor Cortex: Multiple Networks Controlling Multiple Aspects of Behavior

期刊: NEUROSCIENTIST, 2023; ()

The cerebellum and its thalamic projections to the primary motor cortex (M1) are well known to play an essential role in executing daily actions. Anat......

Brain Circuits Underlying Narcolepsy

期刊: NEUROSCIENTIST, 2023; 29 (6)

Narcolepsy is a sleep disorder manifesting symptoms such as excessive daytime sleepiness and often cataplexy, a sudden and involuntary loss of muscle ......

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