期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (3)
Peptides are a rapid-growing class of therapeutics with unique and desirable physicochemical properties. Due to disadvantages such as low membrane per......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (10)
Drug repositioning, also known as drug repurposing, reprofiling, or rediscovery, is considered to be one of the most promising strategies to accelerat......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (4)
Exosomes are extracellular vesicles secreted by cells with a particle size of 30-150 nm in diameter. Exosomes can be used as natural drug carriers. Th......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (4)
Purpose Phosphatidylserine (PS)-deficient small extracellular vesicle (sEV) subpopulations (PS(-) sEVs) circulate in blood for long periods; hence, th......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (3)
Background Gastric cancer (GC) has always been a great threat to human health due to its aggressiveness and lethality. Anlotinib, a novel multi-target......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (5)
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest. While the mechanism of action of CBD in these conditions is ......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (4)
PurposeThe purpose of the present study was to investigate the effect of buffer species on the dissolution profiles of poorly soluble drug salts, focu......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (7)
PurposeThe use of radiolabeled compounds is associated with a number of limitations. Therefore, a new method for the radioisotope-free evaluation of a......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (7)
Objectives Methotrexate (MTX) is subject to therapeutic drug monitoring because of its high pharmacokinetic variability and safety risk outside the th......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (10)
PurposeNew solutions are needed to enable the efficient use of poorly water-soluble drugs. Therefore, we aimed to demonstrate that decreasing particle......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (5)
Bacterial infections in the respiratory tract are considered as one of the major challenges to the public health worldwide. Pulmonary delivery is an a......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (7)
BackgroundLabetalol has an irreplaceable role in treating Hypertensive disorders of pregnancy (HDP), a common disease during pregnancy with a prevalen......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (5)
Biopharmaceuticals have established an indisputable presence in the pharmaceutical pipeline, enabling highly specific new therapies. However, manufact......
期刊： PHARMACEUTICAL RESEARCH, 2023; 40 (6)
ObjectiveBone morphogenetic protein-2 (BMP-2) impacts fertility in women by affecting the menstrual cycle and embryonic development. We aimed to deter......
