期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (2)
We aim to develop a formula based on single nucleotide polymorphisms (SNPs) to predict whether the propofol target-controlled infusion (TCI) concentra......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (2)
Conventional medicines optimisation interventions in people with multimorbidity and polypharmacy are complex and yet limited; a more holistic and inte......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (5-6)
Genes encoding cytochrome P450 enzymes (CYPs) are extremely polymorphic and multiple CYP variants constitute clinically relevant biomarkers for the gu......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (3)
The diagnostic process of familial hypercholesterolemia frequently involves the use of genetic studies. Patients are treated with lipid-lowering drugs......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (1)
Purpose The Pharmacogenomics (PGx) Profile Service was a proof-of-concept project to implement PGx in patient care at Mayo Clinic. Methods Eighty-two ......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (1)
The use of pharmacogenomics in clinical practice is becoming standard of care. However, due to the complex genetic makeup of pharmacogenes, not all ge......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (1)
Virologic failure of antiretroviral therapy (ART) may be explained by single nucleotide polymorphisms (SNPs) in drug absorption and metabolism genes. ......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (4)
Vincristine treatment may cause peripheral neuropathy. In this study, we identified the genes associated with the development of peripheral neuropathy......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (3)
United States clinical practice guidelines for metastatic colorectal cancer recommend use of medications impacted by genetic variants but do not recom......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (5-6)
No biomarkers are available to predict toxicities induced by VEGFR TKIs. This study aimed to identify markers of toxicities induced by these drugs usi......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (2)
Indigenous Australians face a disproportionately severe burden of chronic disease relative to other Australians, with elevated rates of morbidity and ......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (1)
Azathioprine (AZA) and its metabolite, mercaptopurine (6-MP), are widely used immunosuppressant drugs. Polymorphisms in genes implicated in AZA/6-MP m......
期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (4)
Although clozapine is the most effective pharmacotherapy for treatment-resistant schizophrenia, it is under-utilized, and initiation is often delayed.......
