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Defining the contractile prostanoid component in hyperosmolar-induced bronchoconstriction in human small airways

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 168 ()

Exercise-induced bronchoconstriction (EIB) is thought to be triggered by increased osmolarity at the airway epithelium. The aim of this study was to d......

Cross-talk between bioactive lipid mediators and the unfolded protein response in ischemic stroke

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 168 ()

Ischemic cerebral stroke is a severe medical condition that affects about 15 million people every year and is the second leading cause of death and di......

N-glycosylation modifies prostaglandin E2 uptake by reducing cell surface expression of SLCO2A1

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 165 ()

SLCO2A1 functions as a prostaglandin (PG) influx transporter to facilitate intracellular oxidation of PGs and its defect causes dysregulation of PG si......

Conjugated linoleic acid strengthens the apoptotic effect of cisplatin in A549 cells

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 166 ()

One of the chemotherapeutic agents widely used in the treatment of non-small cell lung cancer (NSCLC) is cisplatin. However, the resistance of cancer ......

Uterodilation effect of unripe fruit extract of Crataegus azarolus var. aronia L. on rat uterine smooth muscles

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 169 ()

Crataegus azarolus var. aronia L. (C. aronia) is one of the most important medicinal plants used widely in folk medicine for the prevention of several......

Modulations of urinary lipid mediators in acute bladder cystitis

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 164 ()

Bioactive lipids, such as lysophospholipids, ceramides, and eicosanoids and related mediators, have been demonstrated to be involved in inflammation. ......

The enantioselective separation and quantitation of the hydroxy-metabolites of arachidonic acid by liquid chromatography-tandem mass spectrometry

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 165 ()

Arachidonic acid (AA) is a polyunsaturated fatty acid with a structure of 20:4(omega-6). Cytochrome P450s (CYPs) metabolize AA to several regioisomers......

COX isozymes and non-uniform neoangiogenesis: What is their role in endometriosis?

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 167 ()

This literature review compared the efficacy in of NSAIDs with a placebo in pain relief and disease regression of endometriosis. Despite the poor evid......

Elabela relaxes rat pulmonary artery and trachea via BKCa, KV, and KATP channels

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 167 ()

Objective: Elabela is a newly discovered peptide hormone. This study aimed to determine the functional effects and mechanisms of action of elabela in ......

The association between total cholesterol and cognitive impairment in chronic obstructive pulmonary disease patients

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 164 ()

Aim: Chronic obstructive pulmonary disease (COPD) is primarily a respiratory system disorder associated with extrapulmonary conditions. Cognitive impa......

The effect of SARS-CoV-2 variants on the plasma oxylipins and PUFAs of COVID-19 patients

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 169 ()

Oxylipins are important signalling compounds that are significantly involved in the regulation of the immune system and the resolution of inflammation......

Co-administration of curcumin and polyamines in high-fat diet induced obese rats: Assessment of changes in serum polyamine levels and some tissue parameters

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 169 ()

Obesity is a non-communicable chronic disease that continues to increase around the world. Recently, it has been shown that curcumin positively affect......

Lipid mediated brain disorders: A perspective

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 167 ()

The brain, one of the most resilient organs of the body is highly enriched in lipid content, suggesting the essential role of lipids in brain physiolo......

Endocannabinoid hydrolases differentially distribute in platelets and red blood cells and are differentially released by thrombin

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 164 ()

Background: Plasma levels of the major endocannabinoids 2-arachidonoylgycerol (2AG) and anandamide (Narachidonoylethanolamine, AEA) have been identifi......

Effects of 2-carba-cyclic phosphatidic acid derivatives on IL-1β-stimulated human chondrocytes

期刊: PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2023; 164 ()

Osteoarthritis (OA) is a common joint disease characterized by the breakdown of subchondral bone and cartilage damage, most often affecting middle-age......

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