期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (8)
Forkhead box protein P3 (FOXP3) is known to orchestrate the development and maintenance of T regulatory cells, a cell population specialized in immune......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (6)
The microbial enzyme DapE plays a critical role in the lysine biosynthetic pathway and is considered as a potentially safe antibiotic target. In this ......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Proteins such as enzymes perform their function by predominant non-covalent bond interactions between transiently interacting units. There is an impac......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (1)
Bovine pancreatic trypsin was crystallized, in-complex with Lima bean trypsin inhibitor (LBTI) (Phaseolus lunatus L.), in the form of a ternary comple......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (2)
Cationic helical peptides play a crucial role in applications such as anti-microbial and anticancer activity. The activity of these peptides directly ......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (6)
Inactive rhodopsin can absorb photons, which induces different structural transitions that finally activate rhodopsin. We have examined the change in ......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
The rapid evolution of protein structure prediction tools has significantly broadened access to protein structural data. Although predicted structure ......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Iroquois Homeobox 4 (IRX4) belongs to a family of homeobox TFs having roles in embryogenesis, cell specification, and organ development. Recently, lar......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
The present study endeavors to decode the details of the transcriptional autoregulation effected by the MazE9 antitoxin of the Mycobacterium tuberculo......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Membrane protein-protein interactions are essential for several functions including cell signaling, ion transport, and enzymatic activity. These inter......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Transmembrane proteins are active in amphipathic environments. To stabilize the protein in such surrounding the exposure of hydrophobic residues on th......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Bacterial ribosomes require three initiation factors IF1, IF2, and IF3 during the initial steps of translation. These IFs ensure correct base pairing ......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (6)
Human carnosinases (CNs) are dimeric dipeptidases in the metallopeptidase M20 family. Two isoforms of carnosinases (Zn2+-containing carnosinase 1 (CN1......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; 91 (12)
We present VoroIF-GNN (Voronoi InterFace Graph Neural Network), a novel method for assessing inter-subunit interfaces in a structural model of a prote......
期刊: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2023; ()
Preliminary studies have shown BRCA1 (170-1600) residues to be intrinsically disordered with unknown structural details. However, thousands of clinica......