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Blood proteome of acute intracranial hemorrhage in infant victims of abusive head trauma

期刊: PROTEOMICS, 2023; 23 (3-4)

Abusive head trauma (AHT) is a leading cause of mortality and morbidity in infants. While the reported incidence is close to 40 cases per 100 ' 000 bi......

(Re-)use and (re-)analysis of publicly available metabolomics data

期刊: PROTEOMICS, 2023; 23 (23-24)

Metabolomics, the systematic measurement of small molecules (<1000 Da) in a given biological sample, is a fast-growing field with many different ap......

Proteome of spores from biological indicators in sterilization processes: Bacillus pumilus and Bacillus atrophaeus

期刊: PROTEOMICS, 2023; ()

Bacillus atrophaeus and Bacillus pumilus spores are widely used as biological indicators to assess the effectiveness of decontamination procedures. Sp......

AlphaCutter: Efficient removal of non-globular regions from predicted protein structures

期刊: PROTEOMICS, 2023; 23 (16)

A huge number of high-quality predicted protein structures are now publicly available. However, many of these structures contain non-globular regions,......

Proteome of urticating setae of Ochrogaster lunifer, a processionary caterpillar of medical and veterinary importance, including primary structures of putative toxins

期刊: PROTEOMICS, 2023; 23 (20)

Ochrogaster lunifer (Lepidoptera: Notodontidae) is an Australian processionary caterpillar with detachable urticating setae that have a defensive func......

Rapid and in-depth proteomic profiling of small extracellular vesicles for ultralow samples

期刊: PROTEOMICS, 2023; ()

The integration of robust single-pot, solid-phase-enhanced sample preparation with powerful liquid chromatography-tandem mass spectrometry (LC-MS/MS) ......

A deep learning model for predicting optimal distance range in crosslinking mass spectrometry data

期刊: PROTEOMICS, 2023; 23 (17)

Macromolecular assemblies play an important role in all cellular processes. While there has recently been significant progress in protein structure pr......

Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells

期刊: PROTEOMICS, 2023; 23 (15)

Cancer cachexia is a wasting syndrome characterised by the loss of fat and/or muscle mass in advanced cancer patients. It has been well-established th......

Improving SWATH-MS analysis by deep-learning

期刊: PROTEOMICS, 2023; 23 (9)

Data-independent acquisition (DIA) of tandem mass spectrometry spectra has emerged as a promising technology to improve coverage and quantification of......

Multi-omic analyses and network biology in cardiovascular disease

期刊: PROTEOMICS, 2023; ()

Heart disease remains a leading cause of death in North America and worldwide. Despite advances in therapies, the chronic nature of cardiovascular dis......

Proteomics-based scoring of cellular response to stimuli for improved characterization of signaling pathway activity

期刊: PROTEOMICS, 2023; 23 (5)

Omics technologies focus on uncovering the complex nature of molecular mechanisms in cells and organisms, including biomarkers and drug targets discov......

Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling

期刊: PROTEOMICS, 2023; 23 (18)

Metastatic triple-negative breast cancer (TNBC) has a low 5-year survival rate of below 30% with systemic chemotherapy being the most widely used trea......

The effect of altered pH growth conditions on the production, composition, and proteomes of Helicobacter pylori outer membrane vesicles

期刊: PROTEOMICS, 2023; ()

Gram-negative bacteria release outer membrane vesicles (OMVs) that contain cargo derived from their parent bacteria. Helicobacter pylori is a Gram-neg......

Characterization of outer membrane vesicles released by clinical isolates of Neisseria gonorrhoeae

期刊: PROTEOMICS, 2023; ()

The sexually transmitted pathogen Neisseria gonorrhoeae releases membrane vesicles including outer membrane vesicles (OMVs) during infections. OMVs tr......

Mass spectrometry-based high-throughput proteomics and its role in biomedical studies and systems biology

期刊: PROTEOMICS, 2023; 23 (7-8)

There are multiple reasons why the next generation of biological and medical studies require increasing numbers of samples. Biological systems are dyn......

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