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Precision Medicine and/or Biomarker Based Therapy in T2DM: Ready for Prime Time?

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (3)

Approximately 30-40% of people with type 2 diabetes mellitus develop chronic kidney disease. This is characterised by elevated blood pressure, declini......

Conservative Kidney Management: When, Why, and For Whom?

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (1)

Deciding between dialysis and conservative kidney management (CKM) in an elderly or seriously ill per-son with kidney failure is complex and requires ......

Gut Microbiota-Targeted Interventions in the Management of Chronic Kidney Disease

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (2)

Recent advances in microbiome research have informed the potential role of the gut microbiota in the regulation of metabolic, cardiovascular, and rena......

Flattening the Playing Field for Treatment of Diabetic Kidney Disease

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (3)

Diabetic kidney disease (DKD) remains a major health care issue and is beset with significant racial and ethnic dis-parities in regard to its incidenc......

Teaching Conservative Kidney Management and Other Palliative Care Skills in Nephrology Fellowships

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (1)

Offering and providing effective conservative kidney management (CKM) for patients with end-stage kidney disease who do not want dialysis is a foundat......

Role of Inflammation in Progression of Chronic Kidney Disease in Type 2 Diabetes Mellitus: Clinical Implications

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (3)

Progression of chronic kidney disease in type 2 diabetes has been understood conventionally as a consequence of intraglomerular hemodynamic changes an......

Role of Cell-Based Therapies in T2D

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (3)

Type 2 diabetes mellitus (T2D) has become a global epidemic affecting the health of millions of people. T2D is a complex and multifactorial metabolic ......

Nutrition Management for Chronic Kidney Disease: Differences and Special Needs for Children and Adults

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (4)

Common goals of nutritional therapy across the spectrum of pediatric and adult chronic kidney disease (CKD) include maintaining normal body mass and c......

Congenital Anomalies of the Kidney and Urinary Tract: A Continuum of Care

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (4)

Congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of kidney failure in children and adolescents. CAKUT describes a wi......

Conservative Kidney Management in Kidney

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (1)

Conservative kidney management (CKM) has been increasingly accepted as a therapeutic option for seriously ill patients with advanced chronic kidney di......

Organ Crosstalk Contributes to Muscle Wasting in Chronic Kidney Disease

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (2)

Muscle wasting (ie, atrophy) is a serious consequence of chronic kidney disease (CKD) that reduces muscle strength and function. It reduces the qualit......

Diet and Metabolism in CKD-Related Metabolic Acidosis

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (2)

Metabolic acidosis is a common complication in patients with chronic kidney disease that occurs when the daily nonvolatile acid load produced in metab......

The Role of Dietary Potassium in the Cardiovascular Protective Effects of Plant-Based Diets

期刊: SEMINARS IN NEPHROLOGY, 2023; 43 (2)

Dietary intervention is an essential factor in managing a multitude of chronic health conditions such as cardiovascular and chronic kidney disease. In......

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