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Advantages of the retroperitoneal retrocolic space as the transplant site for encapsulated xenogeneic islets

期刊: XENOTRANSPLANTATION, 2023; 30 (1)

ObjectiveIslet allotransplantation has demonstrated improved clinical outcomes using the hepatic portal vein as the standard infusion method. However,......

Alteration of γδ T cell subsets in non-human primates transplanted with GGTA1 gene-deficient porcine blood vessels

期刊: XENOTRANSPLANTATION, 2023; ()

Background: alpha Gal-deficient xenografts are protected from hyperacute rejection during xenotransplantation but are still rejected more rapidly than......

Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans

期刊: XENOTRANSPLANTATION, 2023; ()

BackgroundPig-derived tissues could overcome the shortage of human donor organs in transplantation. However, the glycans with terminal alpha-Gal and N......

Incidence of serum antibodies to xenoantigens on triple-knockout pig cells in different human groups

期刊: XENOTRANSPLANTATION, 2023; ()

BackgroundXenoantigens other than Gal, Neu5Gc, and Sda may be playing a role in pig graft rejection. We investigated the incidence of antibodies to un......

Antibodies against hyaluronan oligosaccharides in xenotransplantation

期刊: XENOTRANSPLANTATION, 2023; 30 (3)

Carbohydrate-specific antibodies are significant mediators of xenograft rejection. This study analyzed the carbohydrate specificity of antibodies in b......

Glycocalyx dynamics and the inflammatory response of genetically modified porcine endothelial cells

期刊: XENOTRANSPLANTATION, 2023; 30 (5)

Xenotransplantation is a promising approach to reduce organ shortage, while genetic modification of donor pigs has significantly decreased the immunog......

Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain

期刊: XENOTRANSPLANTATION, 2023; ()

Background The shortage of available transplant organs has made it necessary to search for alternatives, one of which is xenotransplantation. However,......

Development of a panel for detection of pathogens in xenotransplantation donor pigs

期刊: XENOTRANSPLANTATION, 2023; ()

There have been high expectations in recent years of using xenotransplantation and regenerative medicine to treat humans, and pigs have been utilized ......

Attitudes of patients with renal disease on xenotransplantation: A systematic review

期刊: XENOTRANSPLANTATION, 2023; 30 (2)

BackgroundRecent years have seen major advancements in xenotransplantation: the first pig-to-human heart transplant, the development of a brain-dead r......

A murine groin site cardiac transplantation model-applicable tool for studying roles of peripheral lymph nodes in transplantation

期刊: XENOTRANSPLANTATION, 2023; ()

The murine heterotopic cardiac transplantation model has been widely used to study antigen-specific immune responses or new immunosuppressive agents, ......

PCR and peptide based PCMV detection in pig - development and application of a combined testing procedure differentiating newly from latent infected pigs

期刊: XENOTRANSPLANTATION, 2023; 30 (4)

Porcine cytomegalovirus (PCMV) is widely distributed in pigs and difficult to detect due to latency. PCMV infection of source pigs was associated with......

Development and characterization of islet-derived mesenchymal stem cells from clinical grade neonatal porcine cryopreserved islets

期刊: XENOTRANSPLANTATION, 2023; ()

Background: Porcine tissues display a great potential as donor tissues in xenotransplantation, including cell therapy. Cryopreserving clinical grade p......

Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs

期刊: XENOTRANSPLANTATION, 2023; 30 (1)

Cardiovascular disease is common and has a high mortality. Due to the limited number of organs available for orthotopic heart transplantation, alterna......

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