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Understanding lncRNA-protein assemblies with imaging and single-molecule approaches

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022; 72 ()

Long non-coding RNAs (lncRNAs) associate with RNA-binding proteins (RBPs) to form lncRNA-protein complexes that act in a wide range of biological proc......

JIF:5.517

Architecture of RNA-RNA interactions

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022; 72 ()

RNA molecules tend to form intricate tertiary structures via intramolecular RNA-RNA interactions (RRIs) to regulate transcription, RNA processing, and......

JIF:5.517

Building the genome architecture during the maternal to zygotic transition

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2022; 72 ()

Proper higher-order chromatin folding can profoundly impact gene expression. In early animal development, chromatin undergoes dramatic reorganization ......

JIF:5.517

LINC complex regulation of genome organization and function

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2021; 67 ()

The regulation of genomic function is in part mediated through the physical organization and architecture of the nucleus. Disruption to nuclear organi......

Making region-specific integumentary organs in birds: evolution and modifications

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2021; 69 ()

Birds are the most diversified terrestrial vertebrates due to highly diverse integumentary organs that enable robust adaptability to various eco-space......

Regulation of 3D chromatin organization by CTCF

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2021; 67 ()

Studies of nuclear architecture using chromosome conformation capture methods have provided a detailed view of how chromatin folds in the 3D nuclear s......

The evolution and genetics of lepidopteran egg and caterpillar coloration

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2021; 69 ()

Insect colors and color patterns have fascinated biologists for centuries. While extensive research has focused on the adult colors of Drosophila and ......

Synthetic human embryology: towards a quantitative future

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2020; 63 ()

Study of early human embryo development is essential for advancing reproductive and regenerative medicine. Traditional human embryological studies rel......

Expanded potential: the key to synthetic embryo?

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2020; 64 ()

How does an embryo acquire totipotency and develop into an adult is a fundamental scientific question. Stem cells derived from pre-implantation embryo......

Perspectives on somatic reprogramming: spotlighting epigenetic regulation and cellular heterogeneity

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2020; 64 ()

Induction of pluripotency in somatic cells via ectopic expression of defined factors demonstrates the reversibility of developmental programming, thus......

Haploid pluripotent stem cells: twofold benefits with half the effort in genetic screening and reproduction

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2020; 64 ()

Haploid pluripotent stem cells, which are capable of self-renewal and differentiation into other cell types with only one set of chromosomes, have bee......

Human evolutionary history in Eastern Eurasia using insights from ancient DNA

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2020; 62 ()

Advances in ancient genomics are providing unprecedented insight into modern human history. Here, we review recent progress uncovering prehistoric pop......

Trans-kingdom RNA interactions drive the evolutionary arms race between hosts and pathogens

期刊: CURRENT OPINION IN GENETICS & DEVELOPMENT, 2019; 58-59 ()

Trans-kingdom RNA plays a key role in host-parasite interactions. Hosts export specific endogenous microRNAs (miRNAs) into pathogens to target pathoge......

JIF:5.29

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