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Th1/Th2/Th17 cytokine profile in hepatic cystic Echinococcosis patients with different cyst stages

期刊: PARASITE IMMUNOLOGY, 2021; 43 (7)

Aims The study aimed to investigate possible correlation between expression level of Th1/Th2/Th17-type profile and cyst viability in the systemic and ......

Transcriptional profiling of Microtus fortis responses to S. japonicum: New sight into Mf-Hsp90 alpha resistance mechanism

期刊: PARASITE IMMUNOLOGY, 2021; 43 (8)

Aims: Schistosomiasis is a parasitic disease with a chronic debilitating character caused by parasitic flatworms of the genus Schistosoma. The main di......

Antitumour metastasis and the antiangiogenic and antitumour effects of a Eimeria stiedae soluble protein

期刊: PARASITE IMMUNOLOGY, ; ()

Some protozoa (Plasmodium falciparum, Toxoplasma gondii, etc) are used to treat cancer because they can improve tumour-induced immunosuppression. This......

Association of previous schistosome infection with fatty liver and coronary heart disease: A cross-sectional study in china

期刊: PARASITE IMMUNOLOGY, 2021; 43 (4)

Background More than 11 million people were estimated to have been infected by Schistosoma japonicum in China before the 1950s. However, few studies h......

Recombinant elongation factor 1 alpha of Haemonchus contortus affects the functions of goat PBMCs

期刊: PARASITE IMMUNOLOGY, 2020; 42 (5)

Excretory/secretory proteins of Haemonchus contortus (HcESPs) intermingle comprehensively with host immune cells and modulate host immune responses. I......

Death from an Adult-onset Still's disease triggered by visceral leishmaniasis

期刊: PARASITE IMMUNOLOGY, 2020; 42 (12)

A 24-year-old patient presented with a 4-month-long high-spiking fever, characteristic rash, sore throat and arthralgias. Bone marrow biopsy examinati......

ApoE deficiency promotes hepatic pathology by aggravating Th17/Treg imbalance in murine schistosomiasis japonica

期刊: PARASITE IMMUNOLOGY, 2020; 42 (12)

Aims TheSchistosoma japonicum (S japonicum)-infectedApoEgene deficiency (ApoE(-/-)) mice were used to determine effect of ApoE on hepatic immunopathol......

Improving the immunogenicity and protective efficacy of a whole-killed malaria blood-stage vaccine by chloroquine

期刊: PARASITE IMMUNOLOGY, 0; ()

A whole-killed malaria blood-stage vaccine (WKV) is promising in reducing the morbidity and mortality of malaria patients, but its efficacy needs to b......

The Nrf2 pathway is required for intracellular replication of Toxoplasma gondii in activated macrophages

期刊: PARASITE IMMUNOLOGY, 2019; 41 (5)

Reactive oxygen species (ROS) produced by oxidases and nonenzymatic sources are important for host defence against intracellular pathogens. In this st......

JIF:2.76

Research on the effect and mechanism of antimicrobial peptides HPRP-A1/A2 work against Toxoplasma gondii infection

期刊: PARASITE IMMUNOLOGY, 2019; 41 (5)

With increasing antibiotic resistance and drug safety concerns, novel therapeutics are urgently needed. Antimicrobial peptides are promising candidate......

JIF:2.76

Y75B8A.8 (HC8) protein of Haemonchus contortus: A functional inhibitor of host IL-2

期刊: PARASITE IMMUNOLOGY, 2019; 41 (7)

Interleukin 2 (IL-2) is an important immune regulatory factor in the immune response of the host. However, little is known about the inhibitor of host......

JIF:2.76

Administration of anti-CTLA-4 monoclonal antibody augments protective immunity induced by Schistosoma japonicum glutathione-S-transferase

期刊: PARASITE IMMUNOLOGY, 2019; 41 (8)

Aims The aim of this study was to evaluate the effect of anti-CTLA-4 monoclonal antibody (mAb) on 26-kDa glutathione-S-transferase (GST) vaccine-induc......

JIF:2.76

KLF4 upregulation is involved in alternative macrophage activation during secondary Echinococcus granulosus infection

期刊: PARASITE IMMUNOLOGY, 2019; 41 (10)

The objective of this study was to investigate macrophage polarization during the early stages of secondary Echinococcus granulosus sensu lato (E. gra......

JIF:2.76

NP30 stimulates Th17 differentiation through DC in Schistosomiasis Japonicum

期刊: PARASITE IMMUNOLOGY, 2018; 40 (5)

The murine monoclonal anti-idiotypic antibody, NP30, is a potential vaccine candidate against Schistosoma japonicum. Previous studies have revealed th......

JIF:2.76

Antinuclear antibodies and interleukin responses in patients with Schistosoma japonicum infection

期刊: PARASITE IMMUNOLOGY, 2018; 40 (10)

Schistosomiasis poses a serious threat to public health, and the infection will develop into chronic and advanced late-stage disease if not treated. A......

JIF:2.76

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