期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Aidi Injection (ADI), a Chinese herbal preparation with anti-cancer activity, is used for the treatment of hepatocellular carcinoma (HCC). ......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Subtilisin QK is a serine protease in the subtilisin family, and is fermented by Bacillus subtilis QK02. The fibrinolytic activity of subti......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background We aim to develop a population pharmacokinetics (PopPK) model of vancomycin for the treatment of septicemia in infants younger than one yea......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Objective In this work, we investigated the effects of gambogic acid (GA) on lipopolysaccharide (LPS)-induced apoptosis and inflammation in a cell mod......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Helicobacter pylori (H. pylori) is a common pathogen in development of peptic ulcers with pyroptosis. Rabeprazole, a critical component of ......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background There are no reports on the incidence of chronic mercury poisoning in a large population in China. This study investigated the epidemiology......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background The objective of the present study was to determine the effect of allisartan, a new angiotensin II type 1 receptor antagonist on vascular r......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stres......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Taurochenodeoxycholic acid (TCDCA) is one of the major active components in bile acid. It was proven to have inhibitory activities on infla......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Low dose of NP exposure can alter adipose tissue formation, and the intake of high-fat diet (HFD) can also lead to the fatty liver disease.......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background: Acute kidney injury (AKI) is associated with significant increases in short- and long-term morbidity and mortality. Drug-induced AKI is a ......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background: Chronic post-surgical pain (CPSP) has a negative impact on the recovery, quality of life, and physical functioning of elderly patients. Th......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background This study aimed to confirm the cytotoxicity of zymosan in vitro and in vivo and determine the appropriate treatment time and the dose of z......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type......
期刊： BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1)
Background The development of novel and effective drugs for targeted human hepatocellular carcinoma still remains a great challenge. The alkaloid niti......
