期刊: MOLECULAR BIOLOGY, 2021; 55 (2)
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Alpha-synuclein misfolding and aggregation resulting in neurototoxicity......
期刊: MOLECULAR BIOLOGY, 2021; 55 (4)
Non-small cell lung cancer (NSCLC) is prevalent worldwide and has a high mortality rate. Even if mesenchymal stem cells (MSCs) are suggested as cancer......
Disulfide bridges are essential for maintaining the structure and function of proteins. Traditionally, studies of the disulfide bonds require expensiv......
期刊: MOLECULAR BIOLOGY, 2021; 55 (1)
The study aimed to investigate tissue-specific gene expression of ABCA1 and ABCG1, encoding cholesterol transporters, as well as PPARG, LXR beta (NR1H......
期刊: MOLECULAR BIOLOGY, 2021; 55 (1)
To determine how nuclease deactivated Cas9 (dCas9) or single-guide RNA (sgRNA) expression levels affect the knockdown efficiency of CRISPRi, we create......
期刊: MOLECULAR BIOLOGY, 2020; 54 (3)
TWIK-related acid-sensitive potassium channel-1 (TASK-1) is a "leak" potassium channel sensitive to extracellular protons. It contributes to setting t......
期刊: MOLECULAR BIOLOGY, 2020; 54 (3)
Homology-directed (HD) genome modification offers an opportunity to precisely modify the genome. Despite reported successful cases, for many loci, pre......
期刊: MOLECULAR BIOLOGY, 2020; 54 (3)
Potassium (K+) deficiency in the soil may seriously affect the yield and quality of plants, which usually satisfy their potassium requirements by enga......
期刊: MOLECULAR BIOLOGY, 2020; 54 (5)
Conyzasaponins produced by the traditional Chinese herbConyza bliniiare oleanane-type saponins with a wide range of biological activities. Here, we id......
期刊: MOLECULAR BIOLOGY, 2020; 54 (5)
Non-coding RNAs are a class of RNAs with multiple roles in plant life. Covalently closed circular RNA molecules (circRNAs) have been recently shown to......
期刊: MOLECULAR BIOLOGY, 2022; 56 (5)
Human cytomegalovirus (HCMV) DNA and proteins are often detected in malignant tumors, warranting studies of the role that HCMV plays in carcinogenesis......
期刊: MOLECULAR BIOLOGY, 2020; 54 (6)
Abstract- Brassica campestris L. is the important oil-bearing crop in China. Rapeseed cake is the main byproduct of rapeseed oil extraction. As the ma......
期刊: MOLECULAR BIOLOGY, 2020; 54 (6)
In this study, we explored the effects of treating human endometrial cancer cells with gamma-synuclein-specific short hairpin RNA (shRNA) and elucidat......
期刊: MOLECULAR BIOLOGY, 2020; 54 (1)
Lysine succinylation of proteins has potential impacts on protein structure and function, which occurs on post-translation level. However, the informa......
期刊: MOLECULAR BIOLOGY, 2020; 54 (1)
Hepatocellular carcinoma (HCC) is a common malignancy worldwide with poor prognosis and high mortality. The aberrant expression or alteration of micro......