Background and Aims IL-6-induced tumor progression has been well established through the induction of antiapoptotic and proliferative genes. However, ......
Background and Aims Although the prevalence of NAFLD has risen dramatically to 25% of the adult population worldwide, there are as yet no approved pha......
Background and Aims Hepatocyte transplantation has been demonstrated to be effective to treat liver metabolic disease and acute liver failure. Neverth......
Background and Aims Aging exacerbates liver neutrophil infiltration and alcohol-associated liver disease (ALD) in mice and humans, but the underlying ......
Background and Aims NAFLD represents an increasing health problem in association with obesity and diabetes with no effective pharmacotherapies. Growin......
Background and Aims HBV covalently closed circular DNA (cccDNA) is a major obstacle for a cure of chronic hepatitis B. Accumulating evidence suggests ......
Background and Aims Large spontaneous portosystemic shunt (SPSS) is associated with increased risk of HE in patients undergoing transjugular intrahepa......
Background and Aims The mechanisms involved in liver regeneration after partial hepatectomy (pHx) are complicated. Cellular senescence, once linked to......
Background and Aims Although NASH can lead to severe clinical consequences, including cirrhosis and hepatocellular carcinoma, no effective treatment i......
Background and Aims Wilson's disease (WD) is a rare hereditary disorder due to ATP7B gene mutation, causing pathologic copper storage mainly in the li......
Background and Aims Globally, NAFLD is one of the most common liver disorders, with an estimated prevalence rate of more than 30% in men and 15% in wo......