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Visfatin Regulates Inflammatory Mediators in Mouse Intestinal Mucosa Through Toll-Like Receptors Signaling Under Lipopolysaccharide Stress

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2021; 69 (1)

Visfatin is a multifunctional protein involved in inflammatory immune stress. The aim of current study was to explore the role of visfatin in lipopoly......

Functional Characteristics and Application of Mesenchymal Stem Cells in Systemic Lupus Erythematosus

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2021; 69 (1)

Systemic lupus erythematosus (SLE) is a rare, heterogeneous autoimmune and autoinflammatory disease that affects both sexes and all races, although th......

Desloratadine Ameliorates Olfactory Disorder and Suppresses AMPA Receptor GluA1 Expression in Allergic Rhinitis Rat

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020; 68 (1)

Allergic rhinitis (AR) is an IgE-mediated inflammation which causes olfactory dysfunction. Antihistamines have been widely used to treat AR while few ......

In Vitro Immunological Effects of CXCR3 Inhibitor AMG487 on Dendritic Cells

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020; 68 (2)

AMG 487 is the targeted blocker of chemokine receptor CXCR3 and improves inflammatory symptoms by blocking the inflammatory cycle. Here we investigate......

Immune Checkpoint Blockade in Cancer Immunotherapy: Mechanisms, Clinical Outcomes, and Safety Profiles of PD-1/PD-L1 Inhibitors

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020; 68 (6)

Programmed cell death protein 1 (PD-1) and its ligand PD-L1 are critical for the regulation of T cell exhaustion and activity suppression. Tumor cells......

Gene Expression Profiling Studies Using Microarray in Osteoarthritis: Genes in Common and Different Conditions

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020; 68 (5)

Osteoarthritis (OA), which is characterized mainly by cartilage degradation, is the most prevalent joint disorder worldwide. Although OA is identified......

Astragaloside IV Exerts Anti-tumor Effect on Murine Colorectal Cancer by Re-educating Tumor-Associated Macrophage

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2020; 68 (6)

Astragaloside IV (AS-IV) has shown anti-tumorigenic properties in certain cancers for its effect of boosting the body's immune system, but its role in......

Retinoids as an Immunity-modulator in Dermatology Disorders

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2019; 67 (6)

The skin is the largest epithelial surface protecting the body from invading microbes. Vitamin A plays vital roles in the host defence of the skin, in......

JIF:2.88

PD-L1 Ameliorates Murine Acute Graft-Versus-Host Disease by Suppressing Effector But Not Regulatory T Cells Function

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2019; 67 (3)

There is increasing evidence that interaction between programmed death 1 (PD-1) and its ligands PD-1 (PD-L1) plays a critical role in the pathology of......

JIF:2.88

Theaflavin-3, 3 '-Digallate Attenuates Rheumatoid Inflammation in Mice Through the Nuclear Factor-kappa B and MAPK Pathways

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2019; 67 (3)

Rheumatoid arthritis (RA) is a common autoimmune disease which impacts a large number of patients worldwide, and new drugs are required for lower the ......

JIF:2.88

Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2019; 67 (4)

Visfatin is involved in the body's inflammation and immune response. Inflammation could promote, while visfatin may directly or indirectly mitigate th......

JIF:2.88

Baicalin Attenuates Joint Pain and Muscle Dysfunction by Inhibiting Muscular Oxidative Stress in an Experimental Osteoarthritis Rat Model

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2018; 66 (6)

Osteoarthritis (OA) is the most common degenerative joint disease, and causes major pain and disability in adults. It has been reported that muscle we......

JIF:2.88

Bindarit Attenuates Pain and Cancer-Related Inflammation by Influencing Myeloid Cells in a Model of Bone Cancer

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2018; 66 (3)

C-C motif chemokine ligand 2 (CCL2) is a small cytokine that functions in inflammation and cancer development. Bindarit, a CCL2 inhibitor, is a small ......

JIF:2.88

Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenograft

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2018; 66 (5)

Xenotransplantation is an attractive solution to the problem of allograft shortage. However, transplants across discordant species barriers are subjec......

JIF:2.88

In Vivo Cardioprotective Effects and Pharmacokinetic Profile of N-Propyl Caffeamide Against Ischemia Reperfusion Injury

期刊: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2017; 65 (2)

Caffeic acid derivatives constitute a class of potent anti-inflammatory and cardioprotective drug candidates. We recently synthesized a new caffeic ac......

JIF:3.02

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