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Challenges in the Implementation of Chronic Obstructive Pulmonary Disease Guidelines in Low- and Middle-Income Countries An Official American Thoracic Society Workshop Report

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (8)

There is a substantial burden of chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), in low- and middle-income count......

Supplementation with Iron in Pulmonary Arterial Hypertension Two Randomized Crossover Trials

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (6)

Rationale: Iron deficiency, in the absence of anemia, is common in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) and is......

Lymphangioleiomyomatosis Association with Underlying Genotype in Patients with Tuberous Sclerosis Complex

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (5)

Rationale: Lymphangioleiomyomatosis (LAM) is a female-predominant lung disease caused by mutations in the tuberous sclerosis complex (TSC) genes TSC1 ......

Mechanical Ventilation Discontinuation Practices in Asia A Multinational Survey

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (8)

Rationale: There are limited data on mechanical discontinuation practices in Asia. Objectives: To document self-reported mechanical discontinuation pr......

COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (7)

Rationale: There is an urgent need for improved understanding of the mechanisms and clinical characteristics of acute respiratory distress syndrome (A......

Pretransplant Risk Factors Can Predict Development of Acute Respiratory Distress Syndrome after Hematopoietic Stem Cell Transplantation

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (6)

Rationale: Acute respiratory distress syndrome (ARDS) is a common complication after hematopoietic stem cell transplantation (HCT) and is a major cont......

Understanding the Host in the Management of Pneumonia An Official American Thoracic Society Workshop Report

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (7)

Pneumonia causes a significant burden of disease worldwide. Although all populations are at risk of pneumonia, those at extremes of age and those with......

Association between a Rapid Reduction in Air Particle Pollution and Improved Lung Function in Adults

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021; 18 (2)

Rationale: Lung function impairment is reportedly associated with elevated exposure to ambient fine particles (particulate matter <= 2.5 mu m in ae......

Protocol and Rationale for the International Lung Screening Trial

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020; 17 (4)

Rationale: The NIST (National Lung Screening Trial) reported a 20% reduction in lung cancer mortality with low-dose computed tomography screening; how......

The Effect of Continuous Positive Airway Pressure on Vascular Function and Cardiac Structure in Diabetes and Sleep Apnea

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020; 17 (4)

Rationale: Although both type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA) are independently recognized as risk factors for cardiovasc......

Temporal Factors and Missed Doses of Tuberculosis Treatment A Causal Associations Approach to Analyses of Digital Adherence Data

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020; 17 (4)

Rationale: Tuberculosis treatment lasts for 6 months or more. Treatment adherence is critical; regimen length, among other factors, makes this challen......

Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020; 17 (7)

Rationale: The current outbreak of coronavirus disease (COVID-19) pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in ......

Methodological Quality of Systematic Reviews and Meta-Analysis on Asthma Treatments A Cross-Sectional Study

期刊: ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020; 17 (8)

Rationale: Systematic reviews (SRs) provide the best evidence of the effectiveness of treatment strategies for asthma. Carefully conducted SRs provide......

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