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Significant Association of Chitinase 3-like 1 Genotypes to Asthma Risk in Taiwan

期刊: IN VIVO, 2021; 35 (2)

Background/Aim: Chitinase 3-like 1 (CHI3L1) is overexpressed in asthma, and negatively associated with forced expiratory volume in the first second. T......

Diabetes Mellitus Causes Male Reproductive Dysfunction: A Review of the Evidence and Mechanisms

期刊: IN VIVO, 2021; 35 (5)

The metabolic disorders caused by diabetes can lead to various complications, including dysfunction of the male reproductive system. In patients with ......

Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng Salvia Miltiorrhiza

期刊: IN VIVO, 2021; 35 (1)

Background: Salvia miltiorrhiza is a medical herb for human disorders including cardiovascular diseases and cancer. However, the interactions between ......

Protective Effects of Baicalin on Arsenic Trioxide-induced Oxidative Damage and Apoptosis in Human Umbilical Vein Endothelial Cells

期刊: IN VIVO, 2021; 35 (1)

Background/Aim: Arsenic trioxide (As2O3) is an environmental pollutant. However, the detailed mechanisms about As2O3-induced loss of endothelial integ......

Ouabain Induces DNA Damage in Human Osteosarcoma U-2 OS Cells and Alters the Expression of DNA Damage and DNA Repair-associated Proteins

期刊: IN VIVO, 2021; 35 (5)

Background/Aim: Ouabain, isolated from natural plants, exhibits anticancer activities; however, no report has presented its mechanism of DNA damage in......

Association of Matrix Metalloproteinase-1 Genotypes With Bladder Cancer Risk

期刊: IN VIVO, 2021; 35 (5)

Aim: There is very little literature reporting the association of matrix metalloproteinase-1 (MMP1) with personal susceptibility to bladder cancer. In......

Drug Screening of Potential Multiple Target Inhibitors for Estrogen Receptor-alpha-positive Breast Cancer

期刊: IN VIVO, 2021; 35 (2)

Background/Aim: Estrogen receptor alpha (ER alpha) antagonist is the most common treatment for ER alpha-positive breast cancer. However, compensatory ......

Finite Element Analysis of an Improved Correction System for Spinal Deformity

期刊: IN VIVO, 2021; 35 (4)

Background/Aim: Surgical treatment for spinal deformity aims to correct malformation, release the nerves, and reconstruct spinal stability. To explore......

Curcumin Activates ROS Signaling to Promote Pyroptosis in Hepatocellular Carcinoma HepG2 Cells

期刊: IN VIVO, 2021; 35 (1)

Background/Aim: Curcumin is a polyphenol that exerts a variety of pharmacological activities and plays an anti-cancer role in many cancer cells. It wa......

A Meta-Analysis for Using Radiomics to Predict Complete Pathological Response in Esophageal Cancer Patients Receiving Neoadjuvant Chemoradiation

期刊: IN VIVO, 2021; 35 (3)

Background: Preservation of organ function is important in cancer treatment. The 'watch-and-wait' strategy is an important approach in management of e......

Comparison of High-flow Nasal Cannula (HFNC) and Conventional Oxygen Therapy in Obese Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis

期刊: IN VIVO, 2021; 35 (5)

Background/Aim: High-flow nasal cannula (HFNC), a new method for postoperative oxygenation, has increasingly received attention during postoperative c......

Anticancer Effect of ERM210 on Liver Cancer Cells Through ROS/Mitochondria-dependent Apoptosis Signaling Pathways

期刊: IN VIVO, 2021; 35 (5)

Background/Aim: Asian Traditional medicines are renowned for their antitumor properties and are efficacious in the clinical treatment of various cance......

Induction of Apoptosis and Inhibition of EGFR/NF-kappa B Signaling Are Associated With Regorafenib-sensitized Non-small Cell Lung Cancer to Cisplatin

期刊: IN VIVO, 2021; 35 (5)

Background/Aim: The combination of regorafenib with cisplatin/pemetrexed has indicated controllable safety and encouraging antitumor activity in non-s......

Deformation of the Pelvic Arteries Caused by Pneumoperitoneum and Postural Changes in an Animal Model

期刊: IN VIVO, 2021; 35 (1)

Background/Aim: We investigated pelvic arterial deformation and shift due to intraoperative pneumoperitoneum and postural changes in an animal model. ......

Traditional Chinese Medicine Brucea Javanica Oil Enhances the Efficacy of Anlotinib in a Mouse Model of Liver-Metastasis of Small cell Lung Cancer

期刊: IN VIVO, 2021; 35 (3)

Background/Aim: Small-cell lung cancer (SCLC) is a recalcitrant disease with liver and other metastasis. The present study evaluated the Efficacy of t......

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