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MicroRNA-432 Acts as a Prognostic Biomarker and an Inhibitor of Cell Proliferation, Migration, and Invasion in Breast Cancer

期刊: CLINICAL BREAST CANCER, 2021; 21 (4)

Breast cancer remains a health burden and the role of miR-432 in breast cancer remains elusive. The clinical study in 117 breast cancer patients and c......

First-line Treatment with Ribociclib plus Endocrine Therapy for Premenopausal Women with Hormone-receptor-positive Advanced Breast Cancer: A Cost-effectiveness Analysis

期刊: CLINICAL BREAST CANCER, 2021; 21 (4)

We conducted a cost-effectiveness analysis incorporating recent phase III clinical trial (MONALEESA-7) data to evaluate the cost-effectiveness of ribo......

Nomogram Predicting the Risk of Locoregional Recurrence After Mastectomy for Invasive Micropapillary Carcinoma of the Breast

期刊: CLINICAL BREAST CANCER, 2021; 21 (4)

Invasive micropapillary carcinoma is a highly aggressive histologic subtype of breast cancer. A total of 388 patients with breast invasive micropapill......

Impact of ESR1 Polymorphisms on Risk of Breast Cancer in the Chinese Han Population

期刊: CLINICAL BREAST CANCER, 2021; 21 (3)

The estrogen receptor-1 (ESR1) gene encodes estrogen receptor-alpha, which is a major biomarker in the development of breast cancer. Through case-cont......

A Retrospective Analysis of the Relationship Between the Result of BRCA1/2 Genetic Testing and Surgical Method Selection in Japan

期刊: CLINICAL BREAST CANCER, 2021; 21 (1)

This study examined the relationship between BRCA1/2 genetic testing results and surgical method selection in patients with primary unilateral breast ......

Radiomic Nomogram for Pretreatment Prediction of Pathologic Complete Response to Neoadjuvant Therapy in Breast Cancer: Predictive Value of Staging Contrast-enhanced CT

期刊: CLINICAL BREAST CANCER, 2021; 21 (4)

This study retrospectively analyzed 215 patients to develop and validate a radiomic nomogram based on staging contrast-enhanced computed tomography fo......

Primary Trastuzumab Resistance After (Neo) adjuvant Trastuzumab-containing Treatment for Patients With HER2-positive Breast Cancer in Real-world Practice

期刊: CLINICAL BREAST CANCER, 2021; 21 (3)

Primary trastuzumab resistance after (neo)adjuvant trastuzumab is an important but tough issue. We conducted a retrospective analysis including 1096 p......

MR Elastography of the Breast: Evolution of Technique, Case Examples, and Future Directions

期刊: CLINICAL BREAST CANCER, 2021; 21 (1)

Recognizing that breast cancers present as firm, stiff lesions, the foundation of breast magnetic resonance elastography (MRE) is to combine tissue st......

Long-term Survival Comparison of Repeated Breast-conserving Surgery Versus Mastectomy for Patients with DCIS with Ipsilateral Breast Tumor Recurrence: A Real-world Longitudinal Study

期刊: CLINICAL BREAST CANCER, 2021; 21 (4)

Background: Although patients diagnosed with ductal carcinoma in situ (DCIS) harbor excellent overall survival (OS) after breast-conserving therapy, t......

Hormone Receptor and Human Epidermal Growth Factor Receptor 2 Detection in Invasive Breast Carcinoma: A Retrospective Study of 12,467 Patients From 19 Chinese Representative Clinical Centers

期刊: CLINICAL BREAST CANCER, 2020; 20 (1)

To evaluate the current status of hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) detection in China, the data from 12,467 i......

PD-L1 Acts as a Promising Immune Marker to Predict the Response to Neoadjuvant Chemotherapy in Breast Cancer Patients

期刊: CLINICAL BREAST CANCER, 2020; 20 (1)

This research analyzed the clinical value of programmed death ligand 1 positivity in predicting the outcome of patients with breast cancer. The databa......

The Undervalued Effects of Polychlorinated Biphenyl Exposure on Breast Cancer

期刊: CLINICAL BREAST CANCER, 2020; 20 (1)

The incidence of breast cancer across the world has been on the rise in recent decades. Because identified risk factors can only explain a relatively ......

Clinical Characteristics and Outcomes of Single Versus Double Hormone Receptor-Positive Breast Cancer in 2 Large Databases

期刊: CLINICAL BREAST CANCER, 2020; 20 (2)

Hormone receptors (HRs) are important for the management of breast cancer. We evaluated the clinical characteristics and outcomes of single versus dou......

MicroRNA-4472 Promotes Tumor Proliferation and Aggressiveness in Breast Cancer by Targeting RGMA and Inducing EMT

期刊: CLINICAL BREAST CANCER, 2020; 20 (2)

MicroRNA-4472 (miR-4472) was upregulated in breast cancer tissues and correlated with aggressive clinicopathologic features. miR-4472 promotes migrati......

Galactogram Grading System for Identifying Breast Cancer With Nipple Discharge

期刊: CLINICAL BREAST CANCER, 2020; 20 (2)

We aimed to establish a galactogram grading system (GGS) and investigate its role in identifying breast cancer with nipple discharge. A consecutive se......

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