期刊: BIOPHYSICAL JOURNAL, 2022; 121 (1)
The assembly of functional biomolecular condensates often involves liquid-liquid phase separation (LLPS) of proteins with multiple modular domains, wh......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (13)
Endothelin-1 and -3 (ET1 and ET3) are potent vasoconstricting isopeptides that are involved in the pathophysiology of various diseases, such as cardio......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (14)
The homodimerization of CD44 plays a key role in an intercellular-to-extracellular signal transduction and tumor progression. Acylated modification an......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (11)
In the erythrocyte membrane, the interactions between glycophorin A (GPA) and Band 3 are associated strongly with the biological function of the membr......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (22)
The antimicrobial peptide, melittin, is a potential next-generation antibiotic because melittin can spontaneously form pores in bacterial cell membran......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (4)
DNA supercoils are generated in genome regulation processes such as transcription and replication and provide mechanical feedback to such processes. U......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (8)
The DNA damage response is a highly orchestrated process. The involvement of the DNA damage response factors in DNA damage response depends on their b......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (12)
A quantitative understanding of how cells interact with their extracellular matrix via molecular bonds is fundamental for many important processes in ......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (16)
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) form the SNARE com-plex to mediate most fusion events of the secretory......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (9)
In epithelial tumors, oncoprotein E6 binds with the ubiquitin ligase E6AP to form E6/E6AP heterodimer; then this heterodimer recruits p53 to form E6/E......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (24)
Zika virus (ZIKV) is a positive-sense single-stranded RNA virus that infects humans and can cause birth defects and neurological disorders. Its non-st......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (21)
The rhodopsin mimic is a chemically synthetized complex with retinyl Schiff base (RSB) formed between pro-tein and the retinal chromophore that can mi......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (7)
Recent evidence has demonstrated that, when cultured on micro-patterned surfaces, living cells can move in a coordinated manner and form distinct migr......
期刊: BIOPHYSICAL JOURNAL, 2022; 121 (12)
Living systems operate far from thermodynamic equilibrium, which usually manifests as broken detailed balance at the molecular scale. At larger scales......