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Discovery of 4H-thieno[3,2-b]pyrrole derivatives as potential anticancer agents

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (8)

In this study, we describe the discovery of the 4H-thieno[3,2-b]pyrrole derivatives as an useful scaffold to obtain potent lead compounds for the trea......

Synthesis and antitumor activity of novel pyridino[2,3-d]pyrimidine urea derivatives

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (8)

A series of novel N-(3-((6-bromopyrido[2,3-d]pyrimidin-4-yl)oxy)phenyl)pyrrolidine-1-carboxamide and 1-(3-((6-bromopyrido[2,3-d]pyrimidin-4-yl)oxy)phe......

Design, syntheses and antitumor activities evaluation of 1,5-diaryl substituted pyrazole secnidazole ester derivatives

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (8)

According to the drug hybridization principle, a series of novel 1,5-diaryl substituted pyrazole secnidazole ester derivatives (6aa-6gc) have been syn......

Catalyst-free synthesis of quinazolinones by oxidative cyclization under visible light in the absence of additives

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (7)

A general metal-free oxidative cyclization route was developed to synthesize quinazolinones under visible light. A series of substituted 2-aminobenzam......

One-pot rapid synthesis of 4H-1-benzopyran derivatives in a deep eutectic solvent

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (8)

A method for introducing a biologically active heterocycle, 2-methylquinoline into the 4-position of a 2-amino-4H-1-benzopyran skeleton is described. ......

Synthesis of methyl 1,5-diaryl-1H-pyrrole-2-carboxylates via acid-catalyzed ring-opening/ring-closure sequence

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (9)

A facile synthesis of methyl 1,5-diaryl-1H-pyrrole-2-carboxylates was reported in this article. Acid-catalyzed reaction of methyl 2-aroyl-1-phenoxycyc......

Design, synthesis, and insecticidal activities of novel diamide derivatives with alpha-amino acid subunits

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (7)

A series of diamide derivatives containing alpha-amino acids were designed and synthesized. These compounds were evaluated for their insecticidal acti......

Green synthesis and anticancer activity of tetrahydrodipyrazolo[3,4-b:4 ',3 '-e]pyridines catalyzed by phospho sulfonic acid

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, ; ()

Biologically portent/significant tetrahydrodipyrazolo[3,4-b:4 ',3 '-e]pyridines are synthesized by an efficient green synthesis of various aldehydes w......

One-pot two-step synthesis of fused thiazinofuranone linked geminal bis 1,2,3-triazole hybrids and their in vitro cytotoxic screening

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, ; ()

In this study, a series of novel geminal bis 1,2,3-triazoles linked to 2H-furo[2,3-d][1,3]thiazine-2,4,5(1H,6H)-trione (3a-3m) were prepared in one po......

An efficient construction of C-N bond under catalyst-free and room temperature conditions

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, ; ()

An efficient and facile process for the construction of C-N bond from 1,6-conjugate addition reaction of 4-arylidene-2,6-di-tert-butylcyclohexa-2,5-di......

Recent achievements on the agricultural applications of thioether derivatives: A 2010-2020 decade in review

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, ; ()

Thioether derivatives, an important synthetic strategy in drug discovery, are acquiring more importance in plant protection field in recent years beca......

A straightforward route to alkyl 5-arylthiophene-2-thiocarboxylates from alkyl 2-aroyl-1-chlorocyclopropanecarboxylates

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021; 58 (3)

In this article, a direct synthetic method for alkyl 5-arylthiophene-2-thiocarboxylates was reported. Treatment of alkyl 2-aroyl-1-chlorocyclopropanec......

Three-component reaction for synthesis of2-amino-6-aryl-5-(phenylamino)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one derivatives in water

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020; 57 (9)

A new three-component domino reaction for the synthesis of 2-amino-6-aryl-5-(phenylamino)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one derivatives4usi......

Trifluoroborane catalyzed chemoselective synthesis of highly functionalized 1,3-thiazin-2-ylidenes

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020; 57 (9)

An efficient chemoselective synthesis of 1,3-thiazine-2-ylidenes was achieved via annulations of beta-aroyl-thioacetamide with propargyl alcohols usin......

Regioselectiveaza-Michaeladditions of2-arylidene-1,3-diphenylpropan-1,3-diones with isatins: Synthesis ofN-diketone-functionalized isatins

期刊: JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020; 57 (10)

The efficient aza-Michael additions of isatins to 2-arylidene-1,3-diphenylpropan-1,3-diones at room temperature in the presence of cesium carbonate ar......

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