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CircSLC7A6 promotes the progression of Wilms' tumor via microRNA-107/ABL proto-oncogene 2 axis

期刊: BIOENGINEERED, 2022; 13 (1)

The dysregulation of circular RNAs (circRNAs) has been proved to be involved in the carcinogenesis of various cancers. Nevertheless, the biological fu......

JIF:3.237

Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis

期刊: BIOENGINEERED, 2022; 13 (1)

Rheumatoid arthritis (RA) is an autoimmune disease caused by synovitis. Two genes, KLF10 (Kruppel like factor 10) and PDZ and LIM domain containing pr......

JIF:3.237

MicroRNA-128-3p suppresses interleukin-1 beta-stimulated cartilage degradation and chondrocyte apoptosis via targeting zinc finger E-box binding homeobox 1 in osteoarthritis

期刊: BIOENGINEERED, 2022; 13 (1)

Accumulating studies have suggested that microRNAs (miRNAs) play vital roles in the pathogenesis of osteoarthritis (OA). Nevertheless, the specific fu......

JIF:3.237

Knockdown long non-coding RNA HCP5 enhances the radiosensitivity of esophageal carcinoma by modulating AKT signaling activation

期刊: BIOENGINEERED, 2022; 13 (1)

Recently, long noncoding RNAs (lncRNAs) have been revealed to participate in cancer therapy. Especial in tumor radiotherapy, lncRNAs usually could enh......

JIF:3.237

Metformin attenuates high glucose-induced injury in islet microvascular endothelial cells

期刊: BIOENGINEERED, 2022; 13 (2)

As one of the most frequently prescribed antidiabetic drugs, metformin can lower glucose levels, improve insulin resistance manage body weight. Howeve......

JIF:3.237

tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A)

期刊: BIOENGINEERED, 2022; 13 (2)

Breast cancer (BC) is a serious threat to female health. tRNA-derived fragments (tRFs) are popular biomarkers for the diagnosis and treatment of cance......

JIF:3.237

2-Methoxyestradiol combined with ascorbic acid facilitates the apoptosis of chronic myeloid leukemia cells via the microRNA-223/Fms-like tyrosine kinase 3/phosphatidylinositol-3 kinase/protein kinase B axis

期刊: BIOENGINEERED, 2022; 13 (2)

Chronic myeloid leukemia (CML) is a malignant myeloproliferative tumor. 2-Methoxyestradiol (2-ME) is an endogenous estrogen metabolite that shows effi......

JIF:3.237

LncRNA miR-17-92a-1 cluster host gene (MIR17HG) promotes neuronal damage and microglial activation by targeting the microRNA-153-3p/alpha-synuclein axis in Parkinson's disease

期刊: BIOENGINEERED, 2022; 13 (2)

Long noncoding RNAs (lncRNAs) have been regarded as modulators of neurodegenerative diseases. Here, we addressed the role of lncRNA miR-17-92a-1 clust......

JIF:3.237

Knockdown of circular RNA tousled-like kinase 1 relieves ischemic stroke in middle cerebral artery occlusion mice and oxygen-glucose deprivation and reoxygenation-induced N2a cell damage

期刊: BIOENGINEERED, 2022; 13 (2)

Ischemic stroke (IS) is an essential contributor to the neurological morbidity and mortality throughout the world. The significance of circular RNA to......

JIF:3.237

Human Plasma Metabolomics Identify 9-cis-retinoic Acid and Dehydrophytosphingosine Levels as Novel biomarkers for Early Ventricular Fibrillation after ST-elevated Myocardial Infarction

期刊: BIOENGINEERED, 2022; 13 (2)

The relevant metabolite biomarkers for risk prediction of early onset of ventricular fibrillation (VF) after ST-segment elevation myocardial infarctio......

JIF:3.237

Upregulation of exosomal circPLK1 promotes the development of non-small cell lung cancer through the miR-1294/ high mobility group protein A1 axis

期刊: BIOENGINEERED, 2022; 13 (2)

CircRNAs (circular RNAs) have been implicated in the development and progression of a variety of cancers. The molecular pathways underlying the progre......

JIF:3.237

Differential expression analysis of microRNAs and mRNAs in the mouse hippocampus of post-stroke depression (PSD) based on transcriptome sequencing

期刊: BIOENGINEERED, 2022; 13 (2)

To clarify the differential expressions of microRNAs and mRNAs in a PSD model, this study employed PSD mice for model construction by injecting vasoco......

JIF:3.237

Log (Lactobacillus crispatus/ Gardnerella vaginalis): a new indicator of diagnosing bacterial vaginosis

期刊: BIOENGINEERED, 2022; 13 (2)

To explore a new marker which can detect bacterial vaginosis (BV) with high sensitivity and specificity quantitatively. According to the Nugent Score,......

JIF:3.237

Application of serum exosomal hypoxia-inducible factor-1 alpha (HIF-1 alpha) as potential circulating biomarker for bacterial peritonitis

期刊: BIOENGINEERED, 2022; 13 (2)

Bacterial peritonitis is a severe disease that diagnosis remains challenging for clinicians. Measuring biomarkers might be a rapid diagnostic method. ......

JIF:3.237

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