期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
HKG is the first fully accessible variant database for Hong Kong Cantonese, constructed from 205 novel whole-exome sequencing data. There has long bee......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (2)
Nanopore sequencing, also known as single-molecule real-time sequencing, is a third/fourth generation sequencing technology that enables deciphering s......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (3)
Single-cell RNA sequencing thoroughly quantifies the individual cell transcriptomes but renounces the spatial structure. Conversely, recently emerged ......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
The important role of human microbiome is being increasingly recognized in health and disease conditions. Since microbiome data is typically high dime......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (3)
Temperate phages (active prophages induced from bacteria) help control pathogenicity, modulate community structure, and maintain gut homeostasis. Comp......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
Separase is a protease that performs critical functions in the maintenance of genetic homeostasis. Among them, the cleavage of the meiotic cohesin dur......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
Arsenic (As) is the most ubiquitous toxic metalloid in nature. Microbe-mediated As metabolism plays an important role in global As biogeochemical proc......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
Single-nucleotide polymorphism (SNPs) may cause the diverse functional impact on RNA or protein changing genotype and phenotype, which may lead to com......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (3)
The reconstruction of gene regulatory networks (GRNs) from data is vital in systems biology. Although different approaches have been proposed to infer......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2021; 3 (2)
Eye diseases are remarkably common and encompass a large and diverse range of morbidities that affect different components of the visual system and vi......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2021; 3 (2)
Annotating the functions of gene products is a mainstay in biology. A variety of databases have been established to record functional knowledge at the......