Endochondral bone formation from the growth plate plays a critical role in vertebrate limb development and skeletal homeostasis. Although miR-1 is mai......
Intervertebral disc degeneration is the basic cause of lumbocrural pain, which not only causes pain and but also serious economic burdens on patients.......
Heterotopic ossification (HO) is a pathological bone formation based on endochondral ossification distinguished by ossification within muscles, tendon......
Rationale: The migration of osteoblastic cells to bone formation surface is an essential step for bone development and growth. However, whether the mi......
Background: The presence of depressive symptoms is associated with increasing risks of hip fractures (HFs). However, few studies investigated the long......
The growth of blood vessels and osteogenesis are coupled in bone tissue. A specialized subset of CD31(hi)Endomucinhi (CD31(hi)Emcn(hi)) vascular endot......
Osteoarthritis (OA) is a common joint disease lacking effective treatments. Dexamethasone (Dex) is often used to relieve joint pain. However, the adve......
In the field of joint surgery, the computer-aided design of knee prostheses suitable for the Chinese population requires a large quantity of anatomica......
Objective: To observe the effect of AZD0530 on the progression of knee OA after blocking beta-catenin phosphorylation and then dormancy of the Wnt/bet......
Aims: Mechanical stress overload in the temporomandibular joint (TMJ) is an important cause of TMJ osteoarthritis (TMJOA). Whether secreted frizzled-r......
The treatment of periodontitis-induced alveolar bone defects remains a clinical challenge. The secreted protein pentraxin 3 (PTX3) protects tissue dur......
Objective: The three direct oral anticoagulants (DOAC), rivaroxaban, apixaban and dabigatran have been associated with lower risks of fractures compar......
Fibrous dysplasia (FD) is a rare bone disease caused by GNAS mutation in skeletal stem cells, typically originating from and worsening in childhood. T......
Background: Periodontal ligament stem cells (PDLSCs) play a crucial role in periodontal bone regeneration. Lactate used to be considered a waste produ......
Abnormal Wnt signaling has been shown to be involved in the pathogenesis of temporomandibular joint osteoarthritis (TMJOA). Recent studies demonstrate......