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A far-red hybrid voltage indicator enabled by bioorthogonal engineering of rhodopsin on live neurons

期刊: NATURE CHEMISTRY, 2021; 13 (5)

Membrane potential is a key aspect of cellular signalling and is dynamically regulated by an array of ion-selective pumps and channels. Fluorescent vo......

Switching on prodrugs using radiotherapy

期刊: NATURE CHEMISTRY, 2021; 13 (8)

Chemotherapy is a powerful tool in the armoury against cancer, but it is fraught with problems due to its global systemic toxicity. Here we report the......

Energy funnelling within multichromophore architectures monitored with subnanometre resolution

期刊: NATURE CHEMISTRY, 2021; 13 (8)

The funnelling of energy within multichromophoric assemblies is at the heart of the efficient conversion of solar energy by plants. The detailed mecha......

C-C bond activation enabled by dyotropic rearrangement of Pd(iv) species

期刊: NATURE CHEMISTRY, 2021; 13 (7)

The weak carbon-metal bond combined with the kinetic inertness of the carbon-carbon bond renders metal-catalysed C-C bond activation to be highly chal......

Chemical-mediated translocation in protocell-based microactuators

期刊: NATURE CHEMISTRY, 2021; 13 (9)

Artificial cell-like communities participate in diverse modes of chemical interaction but exhibit minimal interfacing with their local environment. He......

Switching the magnetic hysteresis of an [Fe-ii-NC-W-v]-based coordination polymer by photoinduced reversible spin crossover

期刊: NATURE CHEMISTRY, 2021; 13 (7)

Magnetic bistable materials that feature magnetic hysteresis are comparable to elementary binary units and promising for application in switches and m......

Catalytic reductive desymmetrization of malonic esters

期刊: NATURE CHEMISTRY, 2021; 13 (7)

Desymmetrization of fully substituted carbons with a pair of enantiotopic functional groups is a practical strategy for the synthesis of quaternary st......

Concise, scalable and enantioselective total synthesis of prostaglandins

期刊: NATURE CHEMISTRY, 2021; 13 (7)

Prostaglandins are among the most important natural isolates owing to their broad range of bioactivities and unique structures. However, current metho......

Constructing ion channels from water-soluble alpha-helical barrels

期刊: NATURE CHEMISTRY, 2021; 13 (7)

The design of peptides that assemble in membranes to form functional ion channels is challenging. Specifically, hydrophobic interactions must be desig......

SuFExable polymers with helical structures derived from thionyl tetrafluoride

期刊: NATURE CHEMISTRY, 2021; 13 (9)

Sulfur(vi) fluoride exchange (SuFEx) is a category of click chemistry that enables covalent linking of modular units through sulfur(vi) connective hub......

General synthesis of single-atom catalysts with high metal loading using graphene quantum dots

期刊: NATURE CHEMISTRY, 2021; 13 (9)

Transition-metal single-atom catalysts present extraordinary activity per metal atomic site, but suffer from low metal-atom densities (typically less ......

Aromatic hydrocarbon belts

期刊: NATURE CHEMISTRY, 2021; 13 (5)

Aromatic hydrocarbon belts (AHCBs) have fascinated scientists for over half a century because of their aesthetically appealing structures and potentia......

Free-triplet generation with improved efficiency in tetracene oligomers through spatially separated triplet pair states

期刊: NATURE CHEMISTRY, 2021; 13 (6)

Singlet fission (SF) can potentially boost the efficiency of solar energy conversion by converting a singlet exciton (S-1) into two free triplets (T-1......

Single crystals of mechanically entwined helical covalent polymers

期刊: NATURE CHEMISTRY, 2021; 13 (7)

Single crystals of a helical covalent polymer have been obtained from an achiral monomer through spiroborate formation. Polymerization and crystalliza......

Nitrene-mediated intermolecular N-N coupling for efficient synthesis of hydrazides

期刊: NATURE CHEMISTRY, ; ()

N-N linkages are found in many natural compounds and endow fascinating structural and functional properties. In comparison to the myriad methods for t......

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