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K-80003 Inhibition of Macrophage Apoptosis and Necrotic Core Development in Atherosclerotic Vulnerable Plaques

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (6)

Purpose Macrophage apoptosis coupled with a defective phagocytic clearance of the apoptotic cells promotes plaque necrosis in advanced atherosclerosis......

JIF:2.77

A Bioinformatics Investigation into the Pharmacological Mechanisms of Sodium-Glucose Co-transporter 2 Inhibitors in Diabetes Mellitus and Heart Failure Based on Network Pharmacology

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Diabetes mellitus (DM) is a major risk factor for the development of heart failure (HF). Sodium-glucose co-transporter 2 (SGLT2) inhibitors ha......

JIF:2.77

Rationale and Design of the H-REPLACE Study: Safety and Efficacy of LMWH Versus Rivaroxaban in ChinEse Patients HospitaLized with Acute Coronary SyndromE

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

Background Acute coronary syndrome (ACS) is a serious and life-threatening condition. Anticoagulation during the acute phase of ACS is effective in re......

JIF:2.77

Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3)

Purpose The extent of myocardial fibrosis is closely related to the prognosis of diabetic cardiomyopathy (DCM). Low-intensity pulsed ultrasound (LIPUS......

JIF:2.77

The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

Purpose To determine the association between low molecular weight heparin (LMWH) use and mortality in hospitalized COVID-19 patients. Methods We condu......

JIF:2.77

Extracellular Vesicle-Mediated Vascular Cell Communications in Hypertension: Mechanism Insights and Therapeutic Potential of ncRNAs

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

Hypertension, a chronic and progressive disease, is an outstanding public health issue that affects nearly 40% of the adults worldwide. The increasing......

JIF:2.77

Research Progress on Pulmonary Arterial Hypertension and the Role of the Angiotensin Converting Enzyme 2-Angiotensin-(1-7)-Mas Axis in Pulmonary Arterial Hypertension

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (2)

Pulmonary arterial hypertension (PAH) is a progressive disease with a complex aetiology and high mortality. Functional and structural changes in the s......

JIF:2.77

Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

Purpose Rivaroxaban, an oral anticoagulant, undergoes the metabolism mediated by human cytochrome P450 (CYP). The present study is to quantitatively a......

JIF:2.77

A Non-inferiority, Randomized Clinical Trial Comparing Paclitaxel-Coated Balloon Versus New-Generation Drug-Eluting Stents on Angiographic Outcomes for Coronary De Novo Lesions

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Background Drug-coated balloon (DCB) has been proved efficacy for coronary small vessel disease, but data regarding outcomes of DCB in common de novo ......

JIF:2.77

Colchicine-Containing Nanoparticles Attenuates Acute Myocardial Infarction Injury by Inhibiting Inflammation

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (6)

Purpose Anti-inflammatory therapy is important for reducing myocardial injury after acute myocardial infarction (MI). New anti-inflammatory drugs and ......

JIF:2.77

CD36+/CD61+Microparticles Correlate with the Risk of Percutaneous Cardiac Interventions in Coronary Artery Disease Patients and the Effects of Ticagrelor

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3)

Purpose The CD36 scavenger receptor is a mediator of both atherogenesis and thrombosis. We aimed to investigate the prognostic value of CD36+ micropar......

JIF:2.77

Rationale and Design of the ADIDAS Study: Association Between Dapagliflozin-Induced Improvement and Anemia in Heart Failure Patients

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3)

Background Heart failure (HF) is one of the most serious health concerns worldwide. Anemia is a highly prevalent comorbidity and outcome predictor in ......

JIF:2.77

Mirabegron Ameliorated Atherosclerosis of ApoE(-/-) Mice in Chronic Intermittent Hypoxia but Not in Normoxia

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (5)

Purpose It has been established that obstructive sleep apnea (OSA) is an independent risk factor for atherosclerosis. Chronic intermittent hypoxia (CI......

JIF:2.77

beta-Hydroxybutyrate Exacerbates Hypoxic Injury by Inhibiting HIF-1 alpha-Dependent Glycolysis in Cardiomyocytes-Adding Fuel to the Fire?

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3)

Purpose Ketone body oxidation yields more ATP per mole of consumed oxygen than glucose. However, whether an increased ketone body supply in hypoxic ca......

JIF:2.77

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