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Spectroscopic Quantification of Surfactants in Solid Lipid Nanoparticles

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2020; 15 (1)

Objective Solid lipid nanoparticles (SLN) mainly consist of lipids and surfactants. However, the toxicity of surfactant cannot be ignored, as the surf......

Investigation of Drug-Polymer Miscibility and Solubilization on Meloxicam Binary Solid Dispersion

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2020; 15 (1)

Purpose This work aims to study the solubilizing capacity of solid dispersion technology with three kinds of polymers and explore the factors affectin......

Spectroscopic Analysis and Dissolution Properties Study of Tosufloxacin Tosylate/Hydroxypropyl-beta-Cyclodextrin Inclusion Complex Prepared by Solution-Enhanced Dispersion with Supercritical CO2

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2020; 15 (4)

Purpose The aim of this study was to prepare tosufloxacin tosylate (TFLX) and hydroxypropyl-beta-cyclodextrin (HP-beta-CD) inclusion complexes by solu......

Improving the Solubility and Dissolution of Ibrutinib by Preparing Solvates

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2020; 15 (4)

Purpose This work aims to screen and provide more ibrutinib (IBT) solvates, and further explore the effects of solvates towards the solubility, the di......

Intelligent Classifier: a Tool to Impel Drug Technology Transfer from Academia to Industry

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2019; 14 (1)

Pharmaceutical technology transfer is one of the components of pharmaceutical innovation. Currently, a gap exists in pharmaceutical technology transfe......

JIF:1.45

Improved Bioavailability of Repaglinide by Utilizing Hydrotropy-Solid Dispersing Techniques and Prepared Its Dropping Pills

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Background Repaglinide (RPG), as an antidiabetic drug, belongs to the biopharmaceutics classification system (BCS) class II drugs. Utilizing hydrotrop......

JIF:2.016

Preparation and Characterization of Ibrutinib Amorphous Solid Dispersions: a Discussion of Interaction Force

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

The aim of this study was to improve the solubility and dissolution of Ibrutinib (IBR), a biopharmaceutical classification system (BCS) class II drug,......

JIF:2.016

Redox-Responsive and Electrically Neutral PLGA Nanoparticles for siRNA Delivery in Human Cervical Carcinoma Cells

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Purpose Many non-viral vectors with positive charge and physical encapsulation of siRNA have been reported. However, the studies of non-viral vectors ......

JIF:2.016

Evaluation and Monitoring of the API Content of a Portable Near Infrared Instrument Combined with Chemometrics Based on Fluidized Bed Mixing Process

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Purpose With the promulgation of industry guidelines, near infrared spectroscopy (NIRS) monitoring the uniformity of solid oral preparations has becom......

JIF:2.016

Rapid Determination in the Quality Control of Chinese Patent Medicine

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Purpose Due to the large number of chemical components in Chinese patent medicine, the quality control analysis is faced with greater challenges. Alth......

JIF:2.016

Progress on Pharmaceutical Sciences/Pharmacy Postgraduate Education: a Bibliometric Perspective

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Objective The study quantitatively investigated the related research progress in pharmaceutical sciences/pharmacy education from a bibliometric angle ......

JIF:2.016

Quantitative Analysis of the QMS for Pharmaceutical Manufacturing

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Purpose To propose a statistical methodology for quantitative analysis of the quality management system (QMS) of pharmaceutical manufacturing. Methods......

JIF:2.016

Investigating the Effect of Particle Size on Cellular Uptake by Aggregation-Caused Quenching Probe-Encapsulating Solid Lipid Nanoparticles, Inhaled

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (4)

Solid lipid nanoparticles (SLN) have been intensively exploited as nanocarriers for pulmonary drug delivery. However, no consensus on the underlying m......

JIF:2.016

The Reform of the Orphan Drug Assessment System in China

期刊: JOURNAL OF PHARMACEUTICAL INNOVATION, 2022; 17 (3)

This perspective article provides historical background and current considerations of the regulation of rare diseases and orphan drugs in China, prese......

JIF:2.016

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