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Cardiovascular risk in patients with spondyloarthritis and association with anti-TNF drugs

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Background: Cardiovascular (CVS) diseases are the leading cause of death worldwide and patients with rheumatic diseases have an increased CVS. CVS ris......

Underweight and obesity are strong predictors of clinical outcomes in patients with ankylosing spondylitis: data from the Smart-phone SpondyloArthritis Management System

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Background: The aim of this study was to examine the impact of underweight, overweight and obesity on clinical outcomes and treatment responses to bio......

Impact of immunogenicity on clinical efficacy and toxicity profile of biologic agents used for treatment of inflammatory arthritis in children compared to adults

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

The treatment of inflammatory arthritis has been revolutionised by the introduction of biologic treatments. Many biologic agents are currently license......

Association of C-reactive protein and non-steroidal anti-inflammatory drugs with cardiovascular events in patients with psoriatic arthritis: a time-dependent Cox regression analysis

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Aims: Psoriatic arthritis (PsA) is associated with accelerated atherosclerosis due to underlying inflammation. Whether inflammatory burden and drugs u......

Ultrasonography predicts the results of labial salivary gland biopsy in patients with suspected Sjogren's syndrome: a matrix risk model

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Objective: Although a positive result of labial salivary gland biopsy (LSGB) is critical for the diagnosis of Sjogren's syndrome, rheumatologists pref......

Increased risk of valvular heart disease in patients with ankylosing spondylitis: a nationwide population-based longitudinal cohort study

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Aims: We aimed to evaluate the risk of valvular heart disease (VHD) among patients with ankylosing spondylitis (AS). Methods: This was a population-ba......

Ten-year survival analysis of patients with primary Sjogren's syndrome in China: a national prospective cohort study

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Aims: To investigate the long-term survival of patients with primary Sjogren's syndrome (pSS) in China. Methods: Patients with pSS who fulfilled the 2......

Serum-derived extracellular vesicles inhibit osteoclastogenesis in active-phase patients with SAPHO syndrome

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Objective: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disorder and the underlying pathoge......

Cyclin-dependent kinase 7 (CDK7) is an emerging prognostic biomarker and therapeutic target in osteosarcoma

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Background: Overexpression of cyclin-dependent kinase 7 (CDK7) is a well-known pathogenic feature of various malignancies and a sign of a more dismal ......

Comparative efficacy and safety of Janus kinase inhibitors and biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and network meta-analysis

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Objective: To evaluate the comparative efficacy and safety of Janus kinase (JAK) inhibitors and biological disease-modifying antirheumatic drugs (bDMA......

Associations between glucocorticoids, antiphospholipid antibodies and femur head necrosis in patients with SLE: a directed acyclic graph-based multicentre study

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2021; 13 ()

Background: Osteonecrosis of the femoral head (ONFH) remains a major cause of disability in patients with systemic lupus erythematosus (SLE) and serio......

Tocilizumab in the treatment of severe and refractory parenchymal neuro-Behcet's syndrome: case series and literature review

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2020; 12 ()

Objectives: This study aimed to investigate the efficacy and safety of tocilizumab (TCZ) in severe and refractory parenchymal neuro-Behcet's syndrome ......

Diagnostic utility of whole spine and thoracic spine MRI corner inflammatory lesions in axial spondyloarthritis

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2020; 12 ()

Background: The presence of > 3 corner inflammatory lesions has been proposed as the definition of a positive spinal magnetic resonance imaging (MR......

The contribution of epigenetics to the pathogenesis and gender dimorphism of systemic sclerosis: a comprehensive overview

期刊: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2020; 12 ()

Systemic sclerosis (SSc) is a life-threatening connective tissue disorder of unknown etiology characterized by widespread vascular injury and dysfunct......

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