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Case report of pulmonary metastasis in a male Wistar rat glioblastoma model

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2021; 34 (1)

Glioblastoma (GBM) is a highly aggressive central nervous system cancer. Its extracranial metastases have rarely been reported in the past few decades......

AMPK-mTOR-ULK1-mediated autophagy protects carbon tetrachloride-induced acute hepatic failure by inhibiting p21 in rats

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2021; 34 (1)

Autophagy is a lysosomal-dependent degradation pathway in eukaryotic cells. Recent studies have reported that autophagy can facilitate the activation ......

Pleural translocation and lesions by pulmonary exposed multi-walled carbon nanotubes

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2020; 33 (3)

Carbon nanotubes (CNTs) are recently developed tubular nanomaterials, with diameters ranging from a few nanometers to tens of nanometers, and the leng......

Effects of 4% paraformaldehyde and modified Davidson's fluid on the morphology and immunohistochemistry of Xiang pig testes

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2020; 33 (2)

Modified Davidson's fluid (mDF) is a good fixative for morphological and antigen preservation. However, recent studies have shown that 4% paraformalde......

Effects of aflatoxin B-1 on the cell cycle distribution of splenocytes in chickens

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2019; 32 (1)

The purpose of the present study was to evaluate effects of aflatoxin B-1 (AFB(1)) on the cell cycle and proliferation of splenic cells in chickens. A......

JIF:1.15

Effects of astragalus injection on different stages of early hepatocarcinogenesis in a two-stage hepatocarcinogenesis model using rats

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2019; 32 (3)

To clarify the suppressive effects of astragalus injection (AI) on different stages of early hepatocarcinogenesis induced by weak promotion, SD rats i......

JIF:1.15

Location and dynamic changes of inflammation, fibrosis, and expression levels of related genes in SiO2-induced pulmonary fibrosis in rats in vivo

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2019; 32 (4)

Silicosis is a serious occupational disease characterized by pulmonary fibrosis, and its mechanism and progression have not been fully elucidated yet.......

JIF:1.15

Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2019; 32 (4)

Papillary renal cell carcinoma (PRCC) accounts for about 10 percent of all renal cell carcinomas, and the prognosis is poor for people with advanced d......

JIF:1.15

Proteomics approach to investigate dynamic protein profile involved in high fat diet-induced fatty liver disease in rats

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2019; 32 (4)

Nonalcoholic fatty liver disease (NAFLD) is a disorder of the liver found worldwide. The molecular mechanisms underlying NAFLD initiation and progress......

JIF:1.15

Histopathological and functional changes in a single-dose model of combretastatin A4 disodium phosphate-induced myocardial damage in rats

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2018; 31 (4)

Cardiotoxicity is a concern in the development of microtubule-disassembling agents (MDAs) as vascular-disrupting agents of tumors. This study investig......

JIF:1.15

Generation of a uniform thymic malignant lymphoma model with C57BL/6J p53 gene deficient mice

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2022; 35 (1)

Lymphoma is the third most common cancer diagnosed in children, and T-cell lymphoma has the worst prognosis based on clinical observations. To date, a......

JIF:1.628

LPS-TLR4/MD-2 TNF-alpha signaling mediates alcohol-induced liver fibrosis in rats

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2022; 35 (2)

Liver fibrosis results from liver inflammation and progresses to liver cirrhosis or liver cancer. It is known that nonalcoholic liver disease is media......

JIF:1.628

Nitrite exposure may induce infertility in mice

期刊: JOURNAL OF TOXICOLOGIC PATHOLOGY, 2022; 35 (1)

In the present study, we investigated the potential of nitrite exposure to induce infertility in mice. Adult female C57BL/6J mice were randomly divide......

JIF:1.628

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