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Coagulation Factors and the Risk of Ischemic Heart Disease A Mendelian Randomization Study

期刊: CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2018; 11 (1)

BACKGROUND: Coagulation plays a role in ischemic heart disease (IHD). However, which coagulation factors are targets of intervention is unclear. We as......

JIF:4.86

Association of Genetic Instrumental Variables for Lung Function on Coronary Artery Disease Risk A 2-Sample Mendelian Randomization Study

期刊: CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2018; 11 (4)

BACKGROUND: Lung function, assessed by forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), is inversely associated with coron......

JIF:4.86

Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms

期刊: CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2018; 11 (7)

BACKGROUND: Intracranial aneurysm (IA) is usually a late-onset disease, affecting 1% to 3% of the general population and leading to lifethreatening su......

JIF:4.86

Osteoprotegerin Disruption Attenuates HySu-Induced Pulmonary Hypertension Through Integrin alpha(v)beta(3)FAK/AKT Pathway Suppression

期刊: CIRCULATION-CARDIOVASCULAR GENETICS, 2017; 10 (1)

Background-Pulmonary arterial remodeling characterized by increased vascular smooth muscle proliferation is commonly seen in life-threatening disease,......

JIF:5.66

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