期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2021; 25 (7)
Introduction: Reactive oxygen species (ROS)-mediated inflammation plays a crucial role in ischemic brain injury. Therefore, the activation of the nucl......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2021; 25 (3)
Introduction: Inflammatory bowel disease (IBD) is a systemic disease with immune abnormalities that can affect the entire digestive tract. A high perc......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2020; 24 (9)
Introduction Inflammasomes are central to atherosclerotic vascular dysfunction with regulatory effects on inflammation, immune modulation, and lipid m......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2020; 24 (2)
Introduction: Dipeptidyl-peptidase-4 (DPP-4) is a surface bound ectopeptidase that is commonly known as CD26 or adenosine deaminase binding protein. D......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2020; 24 (3)
Objectives: 10-hydroxydec-2-enoic acid (10-HDA), a unique component of royal jelly existing only in nature, has the potential to promote human health.......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2020; 24 (4)
Objectives: Cepharanthine exhibits a wide range of therapeutic effects against numerous cancers by virtue of its pleiotropic mechanisms. However, ceph......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2020; 24 (7)
Background: Adenosine 2A receptor (A(2A)R) is involved in many physiological and pathological functions and serves as an important drug target. Inhibi......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (11)
Introduction: Inflammation resolution induced by specialized pro-resolving lipid mediators (SPMs) is a new concept. The application of SPMs is a promi......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 0; ()
Introduction: Autoimmune diseases (ADs) are idiopathic and heterogeneous disorders with contentious pathophysiology. Great strides have been made in e......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (2)
Introduction: Fibrotic disorders are a leading cause of morbidity and mortality; hence effective treatments are still vigorously sought. AdipoRs (Adip......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (3)
Introduction: Kelch-like ECH associated protein 1/Nuclear factor erythroid 2-like factor 2 (Keap1-Nrf2) signaling plays a pivotal role in response to ......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (3)
Introduction: Alzheimer's disease (AD) is a neurodegenerative illness with genetic risk as an etiological factor in a subset of cases. In AD with auto......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (5)
Introduction: TANK-binding kinase 1 (TBK1) is vital for the induction of antiviral innate immune responses. Both RNA and DNA viral infection induces T......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2019; 23 (5)
Introduction: Cardiovascular diseases are the leading cause of human death globally. Lipid mediators contribute to the initiation and resolution of in......