期刊： DRUGS IN R&D, 2021; 21 (2)
Introduction Opioids are potent painkillers but can have severe adverse effects in the intensive care unit (ICU). The aim of this study was to compare......
期刊： DRUGS IN R&D, 2019; 19 (3)
Background Two phase I studies assessed the pharmacokinetics of buprenorphine, its metabolite norbuprenorphine, and naloxone following administration ......
期刊： DRUGS IN R&D, 2019; 19 (3)
Background Researchers have long been interested in the potential drug-drug interactions (DDIs) between opioids and benzodiazepines. However, much rem......
期刊： DRUGS IN R&D, 2022; 22 (1)
Background and Objective This study was designed to explore the protective effects of a clinically available NLR family Pyrin domain-containing recept......
期刊： DRUGS IN R&D, 2022; 22 (2)
Background and Introduction SHR6390 is a new developed highly effective and selective small-molecule oral CDK4/6 inhibitor. We aimed to evaluate the e......
期刊： DRUGS IN R&D, 2022; 22 (1)
Objective Our objective was to evaluate the pharmacokinetics and bioequivalence of test and reference (JANUMET(R)) formulations of sitagliptin phospha......
期刊： DRUGS IN R&D, 2022; 22 (4)
Objective We aimed to assess the bioequivalence, safety, and tolerability of Chinese- and French-manufactured Glucophage (R) immediate-release (GIR) t......
期刊： DRUGS IN R&D, 2022; 22 (1)
Objective The purpose of this single-center, randomized, open, two-period, two-sequence crossover, single-dose administration, bioequivalence research......
期刊： DRUGS IN R&D, 2022; 22 (4)
Background Cloperastine is a pivotal antibechic widely prescribed to treat cough caused by respiratory diseases. The present trial evaluated the pharm......
期刊： DRUGS IN R&D, 2022; 22 (1)
Background Urine is conventionally used as a specimen to document diazepam-related crimes; however, few reports have described the pharmacokinetics of......
期刊： DRUGS IN R&D, 2022; 22 (4)
Background and Objectives Aspirin is a common drug for the treatment of pre-eclampsia. We aimed to explore whether quercetin as a supplement to aspiri......
期刊： DRUGS IN R&D, 2022; 22 (1)
Background and Objectives The aim of this study was to evaluate the pharmacokinetics, safety, and tolerability of aclidinium bromide/formoterol fumara......
期刊： DRUGS IN R&D, 2022; 22 (2)
Background and Objective Anemia caused by iron depletion is common in patients with hemodialysis-dependent stage 5 chronic kidney disease (CKD-5HD) pa......
