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FADS1 is a Prognostic Biomarker in Bladder Cancer: A Study Based on TCGA Data

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (8)

Aim and Objective: Fatty acid desaturase 1 (FADS1) has been reported to be a potential biomarker in various cancers. However, no study has explored th......

Exploring the Mechanism of Lingzhu San in Treating Febrile Seizures by Using Network Pharmacology

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (8)

Objective: Lingzhu San (LZS) is a traditional Chinese medicine (TCM) prescription that can be effective in treating febrile seizures (FS) and there ar......

13-lncRNAs Signature to Improve Diagnostic and Prognostic Prediction of Hepatocellular Carcinoma

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (5)

Background: Hepatocellular carcinoma (HCC) is a common type of cancer with a high mortality rate and is usually detected at the middle or late stage, ......

The Identification of Three Key Genes Related to Stemness in Thyroid Carcinoma through Comprehensive Analysis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (3)

Background: Tumor heterogeneity imposes great challenges on cancer treatment. Cancer stem cells (CSCs) are a leading factor contributing to tumor occu......

Recent Advances on Organic Fluorescent Probes for Stimulated Emission Depletion (STED) Microscopy

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (7)

Stimulated emission depletion (STED) microscopy has become a useful tool for visualization and dynamic monitoring at an ultra-high resolution in biolo......

Investigation of Targeting Relationship between Micro-Rna-22 and Vegfr3 in Lung Squamous Cell Carcinoma

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (1)

Aim: The present study explored the clinical significance of microRNA-22 (miR-22) expression in lung squamous cell carcinoma and to explore the target......

Identification of Novel Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma using Bioinformatics Analysis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (9)

Background: Head and neck squamous cell carcinoma (HNSCC) is a common cancer that is characterized by a complex pathogenesis. Only limited data are av......

An E-nose and Convolution Neural Network based Recognition Method for Processed Products of Crataegi Fructus

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (7)

Background: The manual identification of Fructus Crataegi processed products is inefficient and unreliable. Therefore, efficient identification of the......

Lung Nodule Detection using Convolutional Neural Networks with Transfer Learning on CT Images

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (6)

Aim and Objective: Lung nodule detection is critical in improving the five-year survival rate and reducing mortality for patients with lung cancer. Nu......

Receptor Dynamics in Molecular Recognition by Cryo-EM and Molecular Simulation

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (10)

The appropriate selection of initial receptor structure has been the "cornerstone" or foundation of successful structure-based virtual screening (SBVS......

Dynamic Behavior of Biomaterials Uncovered by Cryo-electron Microscopy

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (7)

Structural biology develops rapidly with time. The static structure analysis of biomaterials is not enough to satisfy the studies of their functional ......

Exploration of the Potential Mechanisms of Compounds from Rheum palmatum L. against Chronic Obstructive Pulmonary Disease: A Network Pharmacology Study

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2021; 24 (7)

Background: Rheum palmatum L. (RpL) is a traditional Chinese medicine commonly used clinically. However, there was no systematic research to elucidate......

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