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Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice

期刊: GLIA, 2021; 69 (8)

Growing evidence indicates that innate immune molecules regulate microglial activation in Alzheimer's disease (AD); however, their effects on amyloid ......

Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration

期刊: GLIA, 2021; 69 (5)

Neurotrauma has been recognized as a risk factor for neurodegenerative diseases, and sex difference of the incidence and outcome of neurodegenerative ......

Homogeneity or heterogeneity, the paradox of neurovascular pericytes in the brain

期刊: GLIA, 2021; 69 (10)

Pericytes are one of the main components of the neurovascular unit. They play a critical role in regulating blood flow, blood-brain barrier permeabili......

IL-17 signaling induces iNOS plus microglia activation in retinal vascular diseases

期刊: GLIA, 2021; 69 (11)

Activation of microglia and inflammation-mediated vascular damages are suggested to play a decisive role in the pathogenesis of various retinopathies.......

Histamine triggers microglial responses indirectly via astrocytes and purinergic signaling

期刊: GLIA, 2021; 69 (9)

Histamine is a monoaminergic neurotransmitter which is released within the entire brain from ascending axons originating in the tuberomammillary nucle......

Loc680254 regulates Schwann cell proliferation through Psrc1 and Ska1 as a microRNA sponge following sciatic nerve injury

期刊: GLIA, 2021; 69 (10)

Peripheral nerve injury triggers sequential phenotype alterations in Schwann cells, which are critical for axonal regeneration. Long noncoding RNAs (l......

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