期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundCells use signaling protein networks to sense their environment and mediate specific responses. Information about environmental stress is us......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease, and it is a multifactorial disease with no definite diagnost......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundOne of the questions in the design of cancer clinical trials with combination of two drugs is in which order to administer the drugs. This i......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundImproving efficiency of disease diagnosis based on phenotype ontology is a critical yet challenging research area. Recently, Human Phenotype......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundSingle-cell RNA sequencing (scRNAseq) data always involves various unwanted variables, which would be able to mask the true signal to identi......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundSystematic fusion of multiple data sources for Gene Regulatory Networks (GRN) inference remains a key challenge in systems biology. We incor......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundAnti-tumor necrosis factor alpha (TNF- ) therapy has made a significant impact on treating psoriasis. Despite these agents being designed to......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundBiological experiments have confirmed the association between miRNAs and various diseases. However, such experiments are costly and time con......
期刊： BMC SYSTEMS BIOLOGY, 2018; 12 ()
Background: Epilepsy is a neurological disease characterized by unprovoked seizures in the brain. The recent advances in sensor technologies allow res......
期刊： BMC SYSTEMS BIOLOGY, 2018; 12 ()
Background: Microbe plays a crucial role in the functional mechanism of an ecosystem. Identification of the interactions among microbes is an importan......
期刊： BMC SYSTEMS BIOLOGY, 2018; 12 ()
Background: Cancer is one of the leading causes for the morbidity and mortality worldwide. Although substantial studies have been conducted theoretica......
期刊： BMC SYSTEMS BIOLOGY, 2018; 12 ()
Background: Osteoarthritis (OA) is the most common disease of arthritis. Analgesics are widely used in the treat of arthritis, which may increase the ......
期刊： BMC SYSTEMS BIOLOGY, 2018; 12 ()
Background: While there are a large number of bioinformatics datasets for clustering, many of them are incomplete, i.e., missing attribute values in s......
