期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2021; 46 (6)
Historically, ryanodine receptors (RyRs) have presented unique challenges for high-resolution structural determination despite long-standing interest ......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2021; 46 (6)
The evolutionarily conserved Piezo channel family, including Piezo1 and Piezo2 in mammals, serves as versatile mechanotransducers in various cell type......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2021; 46 (3)
Poly(beta-L-malic acid) (PMLA) is a natural polyester produced by numerous microorganisms. Regarding its biosynthetic machinery, a nonribosomal peptid......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (4)
African swine fever virus (ASFV) is the causative pathogen of the recent African swine fever epidemic, with devastating impacts on economy. A recent s......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (6)
Chromatin readers are important intermediaries linking epigenetic information and biological phenotypes. Many diseases are caused by mutations in epig......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (7)
Aging is a major risk factor for numerous human pathologies, including cardiovascular, metabolic, musculoskeletal, and neurodegenerative conditions an......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (8)
Ribosome and protein synthesis lie at the core of cell growth and are major consumers of the cellular budget. Here we review recent progress in the co......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (10)
Two major moieties in genome editing are required for precise genetic changes: the locator moiety for target binding and the effector moiety for genet......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (11)
Long noncoding RNAs (lncRNAs) are crucial regulators in diverse cellular contexts and biological processes. The subcellular localization of lncRNAs de......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (1)
Mitophagy refers to the process of selective removal of damaged or superfluous mitochondria: via the autophagy/lysosome pathway. In the past decade th......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (1)
Netrin is a prototypical axon guidance cue. Structural studies have revealed how netrin interacts with the deleted in colorectal cancer (DCC) receptor......
期刊： TRENDS IN BIOCHEMICAL SCIENCES, 2020; 45 (2)
Recent studies demonstrated that alcohol consumption can induce epigenetic changes in the brain, although the exact mechanism underlying such changes ......
