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Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment

期刊: ANNUAL REVIEW OF IMMUNOLOGY, VOL 39, 2021; 39 ()

Understanding tumor immune microenvironments is critical for identifying immune modifiers of cancer progression and developing cancer immunotherapies.......

Cytokine Regulation and Function in T Cells

期刊: ANNUAL REVIEW OF IMMUNOLOGY, VOL 39, 2021; 39 ()

T lymphocytes, the major effector cells in cellular immunity, produce cytokines in immune responses to mediate inflammation and regulate other types o......

Epigenetic Remodeling in Innate Immunity and Inflammation

期刊: ANNUAL REVIEW OF IMMUNOLOGY, VOL 39, 2021; 39 ()

The innate immune response is a rapid response to pathogens or danger signals. It is precisely activated not only to efficiently eliminate pathogens b......

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